External pancreatic fistulas may follow abdominal surgery or injury. While most respond
to conservative management or endoscopic intervention, others might require surgery
for complete healing. We report four cases of patients with external pancreatic fistulas
that failed to respond to conservative management and drainage. N-butyl-2-cyanoacrylate
surgical glue (Glubran 2) was directly injected into the fistulous tract. The fistulas
closed within 24 hours of the Glubran 2 injection in three cases (75 %). In patients
with external pancreatic fistulas that fail to respond to conservative and endoscopic
drainage, injection of Glubran 2 directly into the fistulous tract may lead to closure,
thus avoiding the need for surgical intervention.
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G. Costamagna, M. D.
Digestive Endoscopy Unit · Università Cattolica del Sacro Cuore · A. Gemelli University
Hospital
Largo A. Gemelli 8 · 00168 Rome · Italy
Fax: +39-06-30156581
Email: gcostamagna@rm.unicatt.it
