Cyclic Trimers of Chiral Furan Amino Acids

Tushar K. Chakraborty; Subhasish Tapadar; T. Venugopal Raju; J. Annapurna; Harjinder Singh

doi:10.1055/s-2004-834807

LETTER

Cyclic Trimers of Chiral Furan Amino Acids

Tushar K. Chakraborty*^a, Subhasish Tapadar^a, T. Venugopal Raju^a, J. Annapurna^a, Harjinder Singh*^b
^a Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)27193108; e-Mail: chakraborty@iict.res.in;
^b Department of Chemistry, Panjab University, Chandigarh 160014, India

Abstract

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Abstract

Chiral furan amino acids were synthesized as novel peptide building blocks. Cyclooligomerization of these monomers by a single-step process led to the selective formation of chiral C₃-symmetric cyclic trimers, which were studied for their structures and properties, like anion binding and antimicrobial activities.

Key words

chiral furan amino acids - anion binding - synthetic receptors - cyclic trimers - antimicrobial

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References

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The details of the biological studies will be published separately.