Zusammenfassung
Primäres Ziel der Hochdruckbehandlung ist die Senkung hypertonieinduzierter kardiovaskulärer
Komplikationen und Senkung der Mortalität bei hoher Lebensqualität. Am Beginn der
therapeutischen Intervention steht die Aufklärung des Patienten über das Krankheitsbild,
seine Ursachen und Komplikationen. Die nichtmedikamentöse Therapie stellt die Basis
jeder therapeutischen Intervention dar, unabhängig vom Hypertonieschweregrad. Im Zentrum
aller Bemühungen zur Veränderung des Lebensstiles stehen dabei Maßnahmen zur Gewichtsnormalisierung.
Die Indikation beziehungsweise der Zeitpunkt des Beginns einer medikamentösen antihypertensiven
Therapie richten sich primär nach dem jeweiligen Risikostatus unter Einbeziehung der
Blutdruckwerte. Aufgrund des hohen psychologischen Stellenwertes einer möglichst geringen
Belastung des Organismus sollte die Therapie mit so wenig einzelnen „Pillen” wie möglich
konzipiert werden und frühzeitig in eine wirkungsvolle Kombinationstherapie münden.
Summary
The primary aims of the treatment of high blood pressure are the reduction of hypertension-induced
cardiovascular complications and the lowering of mortality, while preserving a high
quality of life. The therapeutic intervention begins with the education of the patient
about his/her condition, its causes and complications. Irrespective of the severity
of the hypertension, non-pharmaceutical treatment forms the basis of any therapeutic
intervention. At the centre of efforts to modify the patient's lifestyle are measures
aimed at normalising his/her weight. The indication for, and the timing of, initiation
of pharmaceutical hypertensive therapy is oriented primarily to the risk status prevailing,
with consideration being given to the blood pressure values. In view of the high psychological
value of a lowest possible burdening of the organism, treatment should be designed
to involve as few pills as possible, and should lead on to effective combination therapy
as early as possible.
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Anschrift des Verfassers
Prof. Dr. med. Jürgen Scholze
Medizinische Poliklinik Universitätsmedizin Berlin
Carité Campus Mitte
Luisenstraße 13
10117 Berlin
Fax: 030/450-51490
Email: juergen.scholze@charite.de