Electrochemical Cyclization of Dimethyl Aminomalonates

Abstract

Dimethyl aminomalonates were electrochemically oxidized in methanol to afford the corresponding cyclization products through the formation of carbon-carbon bonds. Optimum yields were obtained when NaCN was utilized as the supporting electrolyte at room temperature. Presumably, the electrooxidation involves a two-electron oxidation process.

Key words

cyclizations - electrochemical oxidations - heterocycles - electron transfer - dimethyl ester

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