Background and study aims: Although hydrophilic guide wires can be used to facilitate stricture cannulation
during endoscopic retrograde cholangiopancreatography (ERCP), some endoscopists avoid
using them because of concerns about wire loss during exchange. There are no data
available on the outcomes of using a short hydrophilic guide wire during ERCP. The
aim of this study was to assess the outcomes of therapeutic ERCP procedures in which
a short, completely hydrophilic guide wire was used exclusively.
Patients and methods: A total of 100 patients undergoing ERCP were studied prospectively. A 0.035-inch,
260-cm long, angled-tip hydrophilic wire (Terumo Glidewire) was used initially. Hydraulic
catheter exchange was performed as follows: during catheter withdrawal the assistant
advanced all the available wire into the catheter; a 12-ml syringe was then attached
to the catheter and water was flushed under pressure to “float the wire” and maintain
its position during catheter removal. Variables evaluated included exchange times
and wire loss rates.
Results: A total of 223 catheter exchanges were performed, 132 (59 %) using the Olympus V-Scope
(which held the wire in 62 % of cases): 15 % of exchanges were with catheters/accessories
designed for short-wire use (Boston Scientific Rapid Exchange Biliary System or Rx
System), and 85 % were with a variety of standard-length accessories. Overall, the
mean exchange time was 26 seconds (range 6 - 90 seconds, standard deviation 12 seconds).
The mean exchange time was faster with the V-Scope and with non-Rx-System accessories.
Wire loss occurred in 5 % of all exchanges. Desired ductal/stricture access was achieved
in all the patients.
Conclusions: Exchange of short hydrophilic wires is quick and reliable. The Olympus V-Scope is
able to hold the wire in some cases. Monorail-type devices and accessories slow catheter
exchange down slightly because hydraulic exchange cannot be performed using these
systems.
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M. D. Topazian, M. D.
Department of Medicine · Division of Gastroenterology and Hepatology · Mayo Clinic
College of Medicine
200 First Street SW · Charlton 8 · Rochester · Minnesota 55905 · USA ·
Fax: +1-507-266-3939
Email: topazian.mark@mayo.edu