RSS-Feed abonnieren
DOI: 10.1055/s-2007-963162
© Georg Thieme Verlag KG Stuttgart · New York
Computertomografisch gesteuerte Interventionen bei Kindern
CT-Guided Interventions in ChildrenPublikationsverlauf
eingereicht: 8.1.2007
angenommen: 15.3.2007
Publikationsdatum:
07. März 2008 (online)

Zusammenfassung
Bei Kindern gilt es, im Rahmen von CT-gesteuerten Interventionen Besonderheiten zu beachten. Aufgrund der fehlenden oder schlecht einzuschätzenden Kooperationsfähigkeit müssen die Eingriffe oft in Analgosedierung oder Allgemeinnarkose erfolgen. Aus Strahlenschutzaspekten ist die Indikation zur CT-gesteuerten Intervention streng zu stellen, wenn möglich, sind nicht strahlenanwendende Verfahren zu bevorzugen. Ferner muss auf eine dosisadaptierte Untersuchung mit sequenziellem Untersuchungsmodus sowie Reduktion der Röhrenspannung und des -stroms, die unter der Strahlendosis diagnostischer Untersuchungen liegen sollte, geachtet werden. Bei männlichen Patienten wird ein Gonadenschutz empfohlen. Entscheidend für die Nadelwahl ist auch die vermutete Tumorentität, da zur Differenzierung von im Kindesalter auftretenden Tumoren (klein-, rund- und blauzellige) neben der Histologie auch immunhistochemische, molekularpathologische und zytogenetische Analysen durchgeführt werden müssen. Neben diagnostischen sind auch therapeutische Interventionen (Drainagen, Injektionstherapien, Neurolyse, Radiofrequenzablation) möglich und operative Eingriffe können vermieden werden. Werden die Indikationsstellung sowie die korrekte Durchführung der Eingriffe beachtet, dann sind CT-gesteuerte Interventionen auch bei pädiatrischen Patienten mit sehr geringem Risiko erfolgreich durchführbar.
Abstract
In pediatric CT-guided interventions specific features have to be taken into account. Due to a lack of cooperation or limited ability to cooperate, procedures are often performed using analgosedation or general anesthesia. To provide radiation protection, justified indication for CT-guided intervention is necessary and sonography and MRI are to be preferred whenever possible. CT examinations also need to be dose-adapted with sequential scanning and a tube voltage and tube current reduction compared to pediatric diagnostic CT studies must be ensured. Gonad shields are recommended for male patients. Biopsy device selection depends on the assumed tumor entity since histology and also immunohistochemical, molecular pathological and cytogenetical analysis are necessary to differentiate pediatric tumors (small, round, blue cell tumors). In addition to diagnostic procedures, therapeutic interventions (drainage, injection therapies, neurolysis, and radiofrequency ablation) can also be used in children and can provide an alternative to surgery in selected cases. With justified indications and precise performance, CT-guided interventions can be successful in pediatric patients with limited risks.
Key words
CT - children - intervention
Literatur
- 1
Bendon A A, Krishnan B S, Korula G.
CT-guided lung biopsies in children: anesthesia management and complications.
Paediatr Anaesth.
2005;
15
321-324
MissingFormLabel
- 2
Kaye R D, Sane S S, Towbin R B.
Pediatric intervention: an update - part I.
J Vasc Interv Radiol.
2000;
11
683-697
MissingFormLabel
- 3
Brenner D, Elliston C, Hall E. et al .
Estimated risks of radiation-induced fatal cancer from pediatric CT.
Am J Roentgenol.
2001;
176
289-296
MissingFormLabel
- 4
Heyer C M, Peters S, Lemburg S. et al .
Einschätzung der Strahlenbelastung radiologischer Thorax-Verfahren: Was ist Nichtradiologen
bekannt?.
Fortschr Röntgenstr.
2007;
179
261-267
MissingFormLabel
- 5
Honnef D, Wildberger J E, Stargardt A. et al .
Mehrschicht-Spiral-CT (MSCT) in der Kinderradiologie: Dosisreduktion bei der Untersuchung
von Thorax und Abdomen.
Fortschr Röntgenstr.
2004;
176
1021-1030
MissingFormLabel
- 6
Honnef D, Wildberger J E, Das M. et al .
Dosisreduzierte 16-Schicht-Multidetektor-Spiralcomputertomographie bei Säuglingen
und Kleinkindern mit bronchoskopischem Verdacht auf vaskulär bedingte Trachealstenosen
- erste klinische Ergebnisse.
Fortschr Röntgenstr.
2006;
178
425-431
MissingFormLabel
- 7
Heyer C M, Lemburg S P, Kagel T. et al .
Evaluation of chronic infectious interstitial pulmonary disease in children by low-dose
CT-guided transthoracic lung biopsy.
Eur Radiol.
2005;
15
1289-1295
MissingFormLabel
- 8
Vock P.
CT dose reduction in children.
Eur Radiol.
2005;
15
2330-2340
MissingFormLabel
- 9
Tschammler A, Kenn W, Dinkel H P. et al .
Individueller Dosisbedarf bei Spiral-CT-Untersuchungen des Abdomens.
Forschr Röntgenstr.
2005;
177
1123-1130
MissingFormLabel
- 10
Nagel H D, Blobel J, Brix G. et al .
5 Jahre Konzertierte Aktion Dosisreduktion CT - was wurde erreicht, was ist noch zu
tun?.
Fortschr Röntgenstr.
2004;
176
1683-1694
MissingFormLabel
- 11
Koller F, Roth J.
Die Bestimmung der effektiven Dosen bei CT-Untersuchungen und deren Beeinflussung
durch Einstellparameter.
Fortschr Röntgenstr.
2007;
179
38-45
MissingFormLabel
- 12
Hohl C, Mahnken A H, Klotz E. et al .
Radiation dose reduction to the male gonads during MDCT: the effectiveness of a lead
shield.
Am J Roentgenol.
2005;
184
128-130
MissingFormLabel
- 13
Schulz T, Bennek J, Schneider J P. et al .
MR-gestützte Interventionen bei Kindern.
Fortschr Röntgenstr.
2003;
175
1673-1681
MissingFormLabel
- 14
Guimaraes A C, Chapchap P, Camargo de B. et al .
Computed tomography-guided needle biopsies in pediatric oncology.
J Pediatr Surg.
2003;
38
1066-1068
MissingFormLabel
- 15
Das D K, Pant C S, Rath B. et al .
Fine-needle aspiration diagnosis of intra-thoracic and intra-abdominal lesions: review
of experience in the pediatric age group.
Diagn Cytopathol.
1993;
9
383-393
MissingFormLabel
- 16
Hoffer F A.
Interventional radiology in pediatric oncology.
Eur J Radiol.
2005;
53
3-13
MissingFormLabel
- 17
Cahill A M, Baskin K M, Kaye R D. et al .
CT-guided percutaneous lung biopsy in children.
J Vasc Interv Radiol.
2004;
15
955-960
MissingFormLabel
- 18
Connolly B L, Chait P G, Duncan D S. et al .
CT-guided percutaneous needle biopsy of small lung nodules in children.
Pediatr Radiol.
1999;
29
342-346
MissingFormLabel
- 19
Wilkinson A G, Paton J Y, Gibson N. et al .
CT-guided 14-G cutting needle lung biopsy in children: safe and effective.
Pediatr Radiol.
1999;
29
514-516
MissingFormLabel
- 20
Hoffer F A, Gow K, Flynn P M. et al .
Accuracy of percutaneous lung biopsy for invasive pulmonary aspergillosis.
Pediatr Radiol.
2001;
31
144-152
MissingFormLabel
- 21
Garrett K M, Hoffer F A, Behm F G. et al .
Interventional techniques for the diagnosis of lymphoma and leukemia.
Pediatr Radiol.
2002;
32
653-662
MissingFormLabel
- 22
Marano I, Belfiore G, Cioffi A. et al .
The use of computed tomography guided needle biopsy in thoracic lesions in childhood.
Radiol Med (Torino).
1995;
90
80-83
MissingFormLabel
- 23
Hugosson C O, Nyman R S, Cappelen-Smith J M. et al .
Ultrasound-guided biopsy of abdominal and pelvic lesions in children. A comparison
between fine-needle aspiration and 1.2 mm-needle core biopsy.
Pediatr Radiol.
1999;
29
31-36
MissingFormLabel
- 24
Sklair-Levy M, Lebensart P D, Applbaum Y H. et al .
Percutaneous image-guided needle biopsy in children - summary of our experience with
57 children.
Pediatr Radiol.
2001;
31
732-736
MissingFormLabel
- 25
Garrett K M, Fuller C E, Santana V M. et al .
Percutaneous biopsy of pediatric solid tumors.
Cancer.
2005;
104
644-652
MissingFormLabel
- 26
Hoffer F A.
Liver biopsy methods for pediatric oncology patients.
Pediatr Radiol.
2000;
30
481-488
MissingFormLabel
- 27
Chang S, Kim S H, Lim H K. et al .
Needle tract implantation after sonographically guided percutaneous biopsy of hepatocellular
carcinoma: evaluation of doubling time, frequency, and features on CT.
Am J Roentgenol.
2005;
185
400-405
MissingFormLabel
- 28
Hussain H K, Kingston J E, Domizio P. et al .
Imaging-guided core biopsy for the diagnosis of malignant tumors in pediatric patients.
Am J Roentgenol.
2001;
176
43-47
MissingFormLabel
- 29
Skoldenberg E G, Jakobson A A, Elvin A. et al .
Diagnosing childhood tumors: A review of 147 cutting needle biopsies in 110 children.
J Pediatr Surg.
2002;
37
50-56
MissingFormLabel
- 30
Hoffer F A, Chung T, Diller L. et al .
Percutaneous biopsy for prognostic testing of neuroblastoma.
Radiology.
1996;
200
213-216
MissingFormLabel
- 31
Feneberg R, Schaefer F, Zieger B. et al .
Percutaneous renal biopsy in children: a 27-year experience.
Nephron.
1998;
79
438-446
MissingFormLabel
- 32
Ahrar K, Himmerich J U, Herzog C E. et al .
Percutaneous ultrasound-guided biopsy in the definitive diagnosis of osteosarcoma.
J Vasc Interv Radiol.
2004;
15
1329-1333
MissingFormLabel
- 33
Early S D, Kay R M, Tolo V T.
Childhood diskitis.
J Am Acad Orthop Surg.
2003;
11
413-420
MissingFormLabel
- 34
Ventura N, Gonzalez E, Terricabras L. et al .
Intervertebral discitis in children: a review of 12 cases.
Int Orthop.
1996;
20
32-34
MissingFormLabel
- 35
Hardaway B W, Hoffer F A, Rao B N.
Needle localization of small pediatric tumors for surgical biopsy.
Pediatr Radiol.
2000;
30
318-322
MissingFormLabel
- 36
Waldhausen J H, Shaw D W, Hall D G. et al .
Needle localization for thoracoscopic resection of small pulmonary nodules in children.
J Pediatr Surg.
1997;
32
1624-1625
MissingFormLabel
- 37
Smith M B, Lobe T E, Schropp K P. et al .
A prospective evaluation of an endoscopic ultrasonic probe to detect intraparenchymal
malignancy at pediatric thoracoscopy.
J Laparoendosc Surg.
1996;
6
233-237
MissingFormLabel
- 38
Gaffke G, Stroszczynski C, Rau B. et al .
CT-gesteuerte Resektion pulmonaler Metastasen.
Fortschr Röntgenstr.
2005;
177
877-883
MissingFormLabel
- 39
Krüger K, Eyl G, Morgenroth C. et al .
Erfolgs- und Komplikationsrate der CT-gesteuerten Markierung pulmonaler Rundherde
mittels Spirale vor videoassistierter thorakoskopischer chirurgischer Resektion (VATS).
Fortschr Röntgenstr.
2006;
178
1250-1254
MissingFormLabel
- 40
Gobien R P, Stanley J H, Schabel S I. et al .
The effect of drainage tube size on adequacy of percutaneous abscess drainage.
Cardiovasc Intervent Radiol.
1985;
8
100-102
MissingFormLabel
- 41
Cahill A M, Baskin K M, Kaye R D. et al .
Transgluteal approach for draining pelvic fluid collections in pediatric patients.
Radiology.
2005;
234
893-898
MissingFormLabel
- 42
Gervais D A, Brown S D, Connolly S A. et al .
Percutaneous imaging-guided abdominal and pelvic abscess drainage in children.
Radiographics.
2004;
24
737-754
MissingFormLabel
- 43
Margau R, Amaral J G, Chait P G. et al .
Percutaneous thoracic drainage in neonates: catheter drainage versus treatment with
aspiration alone.
Radiology.
2006;
241
223-237
MissingFormLabel
- 44
Hawkins J A, Scaife E S, Hillman N D. et al .
Current treatment of pediatric empyema.
Semin Thorac Cardiovasc Surg.
2004;
16
196-200
MissingFormLabel
- 45
Kilic N, Celebi S, Gurpinar A.
Management of thoracic empyema in children.
Pediatr Surg Int.
2002;
18
21-23
MissingFormLabel
- 46
Shankar K R, Kenny S E, Okoye B O. et al .
Evolving experience in the management of empyema thoracis.
Acta Paediatr.
2000;
89
417-420
MissingFormLabel
- 47
Klein J S, Zarka M A.
Transthoracic needle biopsy.
Radiol Clin North Am.
2000;
38
235-266
MissingFormLabel
- 48
Hoffer F A, Bloom D A, Colin A A. et al .
Lung abscess versus necrotizing pneumonia: implications for interventional therapy.
Pediatr Radiol.
1999;
29
87-91
MissingFormLabel
- 49
Frumiento C, Sartorelli K, Vane D.
Complications of splenic injuries: expansion of the nonoperative theorem.
J Pediatr Surg.
2000;
35
788-791
MissingFormLabel
- 50
Wippermann C F, Schofer O, Beetz R. et al .
Renal abscess in childhood: diagnostic and therapeutic progress.
Pediatr Infect Dis J.
1991;
10
446-450
MissingFormLabel
- 51
Bingöl-Kologlu M, Ciftci A O, Senocak M E. et al .
Xanthogranulomatous pyelonephritis in children: diagnostic and therapeutic aspects.
Eur J Pediatr Surg.
2002;
12
42-48
MissingFormLabel
- 52
Jamieson D H, Chait P G, Filler R.
Interventional drainage of appendiceal abscesses in children.
Am J Roentgenol.
1997;
169
1619-1622
MissingFormLabel
- 53
Chung T, Hoffer F A, Lund D P.
Transrectal drainage of deep pelvic abscesses in children using a combined transrectal
sonographic and fluoroscopic guidance.
Pediatr Radiol.
1996;
26
874-878
MissingFormLabel
- 54
Belgith M, Ben Brahim M, Jouini R. et al .
Psoas abscess in children based on a series of 18 cases.
Prog Urol.
2003;
13
1372-1375
MissingFormLabel
- 55
Orlicek S L, Abramson J S, Woods. et al .
Obturator internus muscle abscess in children.
J Pediatr Orthop.
2001;
21
744-748
MissingFormLabel
- 56
Garg N K, Carty H, Walsh H P. et al .
Percutaneous Ethibloc injection in aneurysmal bone cysts.
Skeletal Radiol.
2000;
29
211-216
MissingFormLabel
- 57
Cottalorda J, Bourelle S.
Current treatments of primary aneurysmal bone cysts.
J Pediatr Orthop B.
2006;
15
155-167
MissingFormLabel
- 58
Fischer T, Biedermann T, Hermann K G.
Sakroiliitis bei Kindern mit Spondyloarthropathie: Therapeutischer Effect der CT-gestützten
intraartikulären Kortikosteroid-Injektion.
Fortschr Röntgenstr.
2003;
175
814-821
MissingFormLabel
- 59
Assoun J, Railhac J J, Bonnevialle P. et al .
Osteoid osteoma: percutaneous resection with CT guidance.
Radiology.
1993;
188
541-547
MissingFormLabel
- 60
Gangi A, Dietemann J L, Gasser B. et al .
Interstitial laser photocoagulation of osteoid osteomas with use of CT guidance.
Radiology.
1997;
203
843-848
MissingFormLabel
- 61
Rosenthal D I, Hornicek F J, Torriani M. et al .
Osteoid osteoma: percutaneous treatment with radiofrequency energy.
Radiology.
2003;
229
171-175
MissingFormLabel
- 62
Mahnken A H, Tacke J A, Wildberger J E. et al .
Radiofrequency ablation of osteoid osteoma: initial results with a bipolar ablation
device.
J Vasc Interv Radiol.
2006;
17
1465-1470
MissingFormLabel
- 63
Woertler K, Vestring T, Boettner F. et al .
Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47
patients.
J Vasc Interv Radiol.
2001;
12
717-722
MissingFormLabel
- 64
Martel J, Bueno A, Ortiz E.
Percutaneous radiofrequency treatment of osteoid osteoma using cool-tip electrodes.
Eur J Radiol.
2005;
56
403-408
MissingFormLabel
- 65
Lindner N J, Ozaki T, Roedl R. et al .
Percutaneous radiofrequency ablation in osteoid osteoma.
J Bone Joint Surg Br.
2001;
83
391-396
MissingFormLabel
- 66
Cioni R, Armillotta N, Bargellini I. et al .
CT-guided radiofrequency ablation of osteoid osteoma: long-term results.
Eur Radiol.
2004;
14
1203-1208
MissingFormLabel
- 67
Ghandi S, Meech S J, Puthawala M A. et al .
Combined computed tomography-guided radiofrequency ablation and brachytherapy in a
child with multiple recurrences of Wilms’ tumor.
J Pediatr Hematol Oncol.
2005;
27
377-379
MissingFormLabel
- 68
Brown S D, Sonnenberg van E, Morrison P R. et al .
CT-guided radiofrequency ablation of pediatric Wilms tumor in a solitary kidney.
Pediatr Radiol.
2005;
35
923-928
MissingFormLabel
- 69
Tanelian D, Cousins M J.
Celiac plexus block following high-dose opiates for chronic noncancer pain in a four-year-old
child.
J Pain Symptom Manage.
1989;
4
82-85
MissingFormLabel
- 70
Staats P S, Kost-Byerly S.
Celiac plexus blockade in a 7-year-old child with neuroblastoma.
J Pain Symptom Manage.
1995;
10
321-324
MissingFormLabel
- 71
Berde C B, Sethna N F, Fisher D E. et al .
Celiac plexus blockade for a 3-year-old boy with hepatoblastoma and refractory pain.
Pediatrics.
1990;
86
779-781
MissingFormLabel
- 72
Nordmann G R, Lauder G R, Grier D J.
Computed tomography guided lumbar sympathetic block for complex regional pain syndrome
in a child: a case report and review.
Eur J Pain.
2006;
10
409-412
MissingFormLabel
- 73
Ernst S, Heindel W, Fischbach R. et al .
Komplikationen der CT-gesteuerten lumbalen Sympathikolyse: Eigene Erfahrungen und
Literaturübersicht.
Fortschr Röntgenstr.
1998;
168
77-83
MissingFormLabel
Dr. Dagmar Honnef
Klinik für Radiologische Diagnostik, Universitätsklinikum Aachen
Pauwelsstrasse 30
52057 Aachen
Telefon: ++49/2 41/8 08 83 32
Fax: ++49/2 41/8 08 24 11
eMail: honnef@rad.rwth-aachen.de