Summary
Objectives·.
This work is another step in the development of the circulatory model CARDIOSIM®
and of its model library. Continuous flow assistance is often used to support the
right ventricular failure. Computer simulation is one of the methods to study the
effect of this assistance on the failing ventricle. The purpose of this study was
to evaluate the effect of this support on some hemodynamic variables, when different
right ventricular end-systolic elastance and pump speed values were applied.
Methods:
The rotary blood pump model was included into the software package CARDIOSIM®, which
reproduces the cardiovascular system. Lumped parameters models were used to reproduce
the circulatory phenomena. Variable elastance models reproduced the Starling’s law
of the heartfor both ventricles. In the study right ventricular end-systolic elastance
(EmaxraT) and the rotational speed of the pumptookthree different values. All the other parameters
of the model were constants.
Results:
The rotational speed of the pump had a significant influence on right ventricular
end-diastolic and end-systolic volumes, right atrial pressure (Pra), right ventricular
(Qro) and pump flows. The effects on pulmonary arterial pressure (Pap) were more evident
when the right ventricular end-systolic elastance was low. When the speed of the device
increased the mean value of Pra decreased for each value of EmaxMT. The total flow (Qro + pump flow) increased when the speed of the pump increased.
Conclusions:
Our simulation (in good agreement with the results presented in literature) showed
that Hemo-pump produces a rise in total flow, a drop in blood flow pumped out by the
right ventricle and a drop in right atrial pressure.
Keywords
Mock circulatory system - rotary pump - computer model - hemodynamic
