DOI : 10.1055/s-00000036

Laryngo-Rhino-Otologie

Issue S 02 · Volume 102 · May 2023 DOI: 10.1055/s-013-57506


94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn
Congress Center Leipzig, 17.–20.05.2023

President: Univ.-Prof. Dr. med. Orlando Guntinas-Lichius
Abstracts (HTML) Abstracts (PDF) List of Authors
Affolter, Annette; Scherl, Claudia; Lammert, Anne; Azhakesan, Alexya; Kern, Johann; Fleckenstein, Jens; Rotter, Nicole; Bugia, Luis: PD-L1 expression is associated with senescence in HNSCC cells after irradiation
Betzler, AnnikaC; Strobel, Hannah; Abou, Tsima Kors; Azoitei, Ninel; Greve, Jens; Theodoraki, Marie-Nicole; Schuler, PatrickJ; Laban, Simon; Hoffmann, ThomasK; Grassilli, Emanuela; Brunner, Cornelia: BTK isoforms p80 and p65 are expressed in head and neck squamous cell carcinoma (HNSCC) and involved in tumor progression
Boia, Radu Eugen; Ceausu, Amalia Raluca; Gaje, PusaNela; Boia, Simina: Head and Neck Squamous Cell Carcinomas with E-cadherin Expression and Associated HPV18 infection
Csűry, Dániel Tamás; Eckstein, Markus; Balk, Matthias; Rupp, Robin; Iro, Heinrich; Gostian, Antoniu-Oreste: Computer-assisted Histomorphological Analysis of Head and Neck Carcinomas and its Relevance in the Oncological Outcome
Döscher, Johannes; Currall, Eve; Abou, Tsima Kors; Schuler, Patrik; Laban, Simon; Hoffmann, ThomasK.; Ottensmeier, Christian: Cytotoxic CD4+ T cells decrease under primary chemoradiotherapy of HNSCC
Daser, Anke; Weltermann, Niklas; Bruderek, Kirsten; Lang, Stephan; Brandau, Sven: Correlation of systemic and local inflammation in patients with oropharyngeal carcinoma.
Deuss, Eric; Fehr, Lara; Kahl, Laura; Künzel, Julian; Zimmer, Stefanie; Gül, Désirée; Stauber, Roland; Lang, Stephan; Meyer, Moritz; Brandau, Sven; Hussain, Timon: Intratumoral heterogeneity of PD-L1 expression in head and neck squamous cell cancers and its clinical relevance
Dib, Maria; Busch, Chia-Jung; Justian, Nathanil; Scharf, Christian; Burchardt, Martin; Caetano-Pinto, Pedro: Investigation of Cetuximab Pretreatment Effects on Cisplatin or Sunitinib Cytotoxicity in Head and Neck Carcinoma Cells in vitro.
Fleckner, Jonas; Idel, Christian; Rades, Dirk; Pries, Ralph; Bruchhage, Karl-Ludwig: Alterations of blood monocyte subsets and circulating CD4/CD8 T Cells as bioliquid parameters for prognosis and therapy response prediction in Head and Neck Cancer
Gonzalez, Jose; Rodenburger, Nils; Busch, Chia-Jung; Scharf, Christian: Application of cold atmospheric plasma as an endoscopically based tumour therapy option in the head and neck region
Hillebrand, Johannes Gabriel; Weusthof, Christopher; Kleigrewe, Karin; Wollenberg, Barbara: Smoking and head and neck cancer significantly alters metabolome of platelets
Hofmann, Linda; Waizenegger, Marie; Niesler, Beate; Schuler, PatrickJ; Laban, Simon; Hoffmann, ThomasK; Brunner, Cornelia; Theodoraki, Marie-Nicole: Impact of treatment-primed exosomes from plasma of head and neck cancer patients on the epithelial-to-mesenchymal transition
Huber, Diana; Hofmann, Linda; Lotfi, Ramin; Hoffmann, ThomasK.; Brunner, Cornelia; Theodoraki, Marie-Nicole: Effect of plasma-derived exosomes from HNSCC patients on NF-κB signaling in macrophages
Hussain, Timon; Deuss, Eric; Marchesi, Julian; Lang, Stephan; Brandau, Sven: Differences in microbial colonization in p16-positive and p16-negative oropharyngeal carcinomas
Idel, Christian; vonBernuth, Amelie; Ribbat-Idel, Julika; Pries, Ralph; Perner, Sven; Bruchhage, Karl-Ludwig: TRIM21 as a marker for a worse progression free survival in HNSCC
Kühn, JanPhilipp; Rimbach, Hugo; Berndt, Sabrina; Koerner, Sandrina; Linxweiler, Barbara; Solomayer, Erich-Franz; Wagner, Mathias; Schick, Bernhard; Linxweiler, Maximilian: Preoperative nasal irrigation in patients with tumors of the nasal cavity and paranasal sinuses for non-invasive cytological diagnostics and prediction of the tumor entity
Körner, Sandrina; Kühn, Jan-Philipp; Wemmert, Silke; Schick, Bernhard; Linxweiler, Maximilian: Impact of the SEC62 oncogene on the transcriptome and molecular pathways in head and neck cancer
Kürten, Cornelius; Kulkarni, Aditi; Vujanovic, Lazar; Cillo, AnthonyR.; Bruno, Tullia; Lang, Stephan; Ferris, RobertL.: CD39+ and Tim3+ T reg are potential effector cells in the peripheral blood and tumor microenvironment of head and neck squamous cell carcinoma patients
Kansy, Benjamin; Li, Jing; Lang, Stephan; Ferris, Robert: Treg proliferation in HNC patients is not inhibited through PD1/ PDL1 interaction
Kramer, Benedikt; Knüttel, Manuel; Rotter, Nicole; Scherl, Claudia; Huber, Lena: Effect of small molecule tyrosine kinase inhibitors on TGFß1-expression in HPV-positive and -negative HNSCC
Lammert, Anne; Affolter, Annette; Jungbauer, Frederic; Kern, Johann; Rotter, Nicole; Scherl, Claudia; Tenschert, Esther: Patient-specific spheroids from squamous cell carcinoma of the head and neck region (HNSCC) as a tool for personalized therapy
Lauterbach, Maren; Bashiri, Ali Dezfouli; Ruck, Anne; Multhoff, Gabriele; Wollenberg, Barbara: Overcoming Immune-Escape – Platelet derived vesicles modulate NK cell function
Leichtle, Franziska; Theodoraki, Marie-Nicole; Greve, Jens; Laban, Simon; Schuler, PatrickJ.; Hoffmann, ThomasK.; Cordes, Nils; Brunner, Cornelia: Influence of BTK on EMT, CSC enrichment and immune system/tumor micromilieu in HNSCC
Ludwig, Sonja; Schütz, Julia; Theodoraki, Marie-Nicole; Seiz, Elena; Jungbauer, Frederic; Scherl, Claudia; Lammert, Anne; Rotter, Nicole; Tengler, Luisa: Plasma exosomes from Head and Neck Cancer Patients modulate Immune Checkpoint Receptors on T cells and attenuate the Efficacy of Immunotherapy in vitro
Maas, Philippe Alexander; Klümper, Niklas; Below, Eduard; Strieth, Sebastian; Gredig, Marie Nina; Dietrich, Dimo; Eckrich, Jonas: Examination of three-dimensional xenografts derived from HNSCC and Melanoma cell lines deploying the CAM assay
Meyer, Moritz; Arolt, Christoph; Quaas, Alexander; Nachtsheim, Lisa; Wolber, Philipp; Kansy, Benjamin; Lang, Stephan; Klußmann, JensPeter: Analysis of the expression of LAG3 in the tumor microenvironement of aggressive salivary gland carcinomas
Netzer, Christoph; Weigert, Andreas; Maćinković, Igor; vonArps-Aubert, Vanessa; vonder Grün, Jens; Küffer, Stefan; Beutner, Dirk: Relationships between spatial distribution in the tumour microenvironment and functions of macrophage subtypes in squamous cell carcinomas of the head and neck
Oberste, Maximilian; Simon, Frank; Nierkamp, Inga; Stollenwerk, Verena; Beule, Georg Achim; Rudack, Claudia: Transcriptome analysis using bulk RNA sequencing of adenocarcinomas of the paranasal sinuses compared to healthy turbinate tissue
Quabius, Elgar; Kühnel, André; Laudien, Martin; Hoppe, Florian; Mlysnki, Robert; Hoffmann, Markus: Tonsillar swabs and sputum predict SLPI- and AnxA2 expression in tonsils: A prospective study on smoking dependent SLPI- and AnxA2-expression, and tonsillar HPV infection
Rieckmann, Thorsten; Oetting, Agnes; Christiansen, Sabrina; Gatzemeier, Fruzsina; Bussmann, Lara; Köcher, Sabrina; Böttcher, Arne; Stölzl, Katharina; Hoffmann, Anna-Sophie; Struve, Nina; Kriegs, Malte; Petersen, Cordula; Rothkamm, Kai; Betz, Christian; Zech, Henrike: Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1
Rimbach, Hugo; Kühn, Jan-Philipp; Linxweiler, Barbara; Körner, Sandrina; Wagner, Mathias; Solomayer, Erich-Franz; Schick, Bernhard; Linxweiler, Maximilian: Intraoperative wound irrigation in neck dissections for cytological differential diagnosis and prediction of the presence of lymph node metastases in patients with head and neck squamous cell carcinoma.
Saparinjuk, Anastasia; Birkenhäger, Ralf; Becker, Christoph; Knopf, Andreas: Comparative Analysis of Genexpression of Hypoxiagenes in Pleomorphic adenoma, Carcinoma ex Pleomorphic adenoma and Warthin’s tumour through relative quantification using the Real-time qPCR method
Scheckenbach, Kathrin; Steffan, Florian Paul; Haist, Corinna; Hüsken, Saskia; Bister, Arthur; Wagenmann, Martin; Schipper, Jörg; Wiek, Constanze; Hanenberg, Helmut: Combination of CAR-T cell therapy and BITEs as an optimized treatment strategy for head and neck cancer (HNSCC)
Schmidl, Benedikt; Vossenkämper, Kim-Aylin; Stark, Leonhard; Stögbauer, Fabian; Boxberg, Melanie; Pickhard, Anja; Winter, Christof; Wollenberg, Barbara; Wirth, Markus: The Tumor Immune Microenvironment (TIME) of SCCUP in comparison to oropharyngeal carcinoma
Schmitz, Marie Alina; Weiser, Tobias; Stögbauer, Fabian; Lauterbach, LouiseAnna Maren; Verschoor, Admar; Engelmann, LucaSophie; Wollenberg, Barbara: Head and Neck Squamous cell carcinomas in 3D organotypic co-cultures (OTC)
Schwamborn, Carolin; Böhm, Felix; Alperovich, Anna; Zhang, Xiaohan; Giannantonio, Tommaso; Sommer, Fabian; Hoffmann, ThomasK.; Schuler, PatrickJ.: First results of the ex vivo application and analysis with neural networks in hyperspectral imaging (HSI) of squamous cell carcinoma of head and neck
Seiz, Elena; Azhakesan, Alexya; Weis, Cleo-Aron; Ludwig, Sonja; Schütz, Julia; Huber, Lena; Bieback, Karen; Kern, Johann; Rotter, Nicole; Affolter, Annette: Clinical correlation of HNSCC tissue cultures in the ex-vivo model to predict response to checkpoint inhibitor therapy
Seuthe, Charlott IngaMarte; Schulte, Lukas; Ehrhardt, Anja; Ehrke-Schulz, Eric; Park, J.-H. Jonas: Adenoviral oncolysis in head and neck squamous cell carcinoma
Six, Klara; Kaißer, Carlotta; Götz, Marlies; Greiner, Jochen; Theodoraki, Marie-Nicole; Adrian, v.Witzleben; Laban, Simon; Brunner, Cornelia; Hoffmann, ThomasK.; Schuler, PatrickJ.: The effect of the immune checkpoint inhibitor anti-LAG-3 on antigen-specific T-cells compared with nivolumab in vitro in head and neck cancer
Sonntag, Michael; Laban, Simon; Theodoraki, Marie-Nicole; Schuler, Patrick; Hoffmann, Thomas; Brunner, Cornelia: Analyses of effector and suppressive B cell populations in head and neck tumor bearing mice
Stöth, Manuel; Mack, Patricia; Meyer, Till; Ickrath, Pascal; Gehrke, Thomas; Hagen, Rudolf; Hackenberg, Stephan; Scherzad, Agmal: Tissue-resident memory CD8 T cells as a potential target for immune checkpoint inhibitors in head and neck squamous cell carcinoma
Tengler, Luisa; Schütz, Julia; Tiedtke, Moritz; Jablonska, Jadwiga; Theodoraki, Marie-Nicole; Nitschke, Katja; Weiß, Christel; Seiz, Elena; Affolter, Annette; Jungbauer, Frederic; Lammert, Anne; Rotter, Nicole; Ludwig, Sonja: Stage-dependent Effects of Plasma Exosomes from Head and Neck Cancer Patients on Endothelial Cell Function
Theodoraki, Marie-Nicole; Ezic, Jasmin; Laban, Simon; Schuler, Patrick; Brunner, Cornelia; Niesler, Beate; Hoffmann, Thomas; Hofmann, Linda: Exosomal miRNA and mRNA signatures as liquid biomarker for head and neck cancer
Thierauf, Julia; Kaluziak, Stefan; Codd, Elizabeth; Jobbagy, Soma; Purohit, Rashi; Naranbhai, Vivek; Huang, Mai; Fisch, Adam; Ritterhouse, Lauren; Lennerz, Jochen; Iafrate, John Anthony: Title: Pigmentation status as a Prognostic Biomarker for Survival in Mucosal Melanoma
Ugele, Ines; Wehrstein, Monika; Dettmer, Katja; Symeou, Luisa; Michaelides, Ioannis; Künzel, Julian; Oefner, Peter; Kreutz, Marina; Bohr, Christopher; Renner, Kathrin: Interaction between tumor metabolism and immune infiltrate in HNSCC
Uhl, Bernd; Wu, Zhengquan; Canis, Martin; Gires, Olivier; Reichel, ChristophA.: Cellular senescence as prognostic biomarker and herapeutic target in HNSCC
Wilhelm, Christian; Tirtey, Clara; Ehret, Totta Kasemo; Scherzad, Agmal: Impact of hypoxia and the transcription factors HIF-1α und JMJD1A on the epithelial-mesenchymal transition in head and neck squamous cell carcinoma
Wirth, Markus; Holzmann, Katharina; Kasajima, Atsuko; Mogler, Carolin; Jira, Daniel; Stangl, Stefan; Wollenberg, Barbara; Multhoff, Gabriele: Evaluation of the clinical utility of Hsp70-based intraoperative fluorescence imaging of head and neck cancer
Ziogas, Maria; Balaji, Harini; Siefer, Oliver; Klußmann, Peter Jens; Hübbers, Ulrich Christian: Analysis of cell proliferation caused by oxidative stress, 17ß-estradiol and HPV16-E6*I expression in HPV-positive OPSCC
Rohner, Pauline; Sönnichsen, Rasmus; Hochmuth, Sabine; Radeloff, Andreas: Influence of face masks on speech intelligibility in hearing impaired individuals