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Exp Clin Endocrinol Diabetes 2022; 130(07): 468-474
DOI: 10.1055/a-1543-8559
Article

Idiopathic Frozen Shoulder in Individuals with Diabetes: Association with Metabolic Control, Obesity, Antidiabetic Treatment and Demographic Characteristics in Adults with Type 1 or 2 Diabetes from the DPV Registry

Alexander J. Eckert 
1   Institute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany
2   German Centre for Diabetes Research (DZD), Munich-Neuherberg, Germany
,
Maike Plaumann
3   Diabetologische Schwerpunktpraxis Hannover, Hannover, Germany
,
Sigrid Pehlke
4   PDG Praxisgemeinschaft, Idar-Oberstein, Germany
,
Christof Beck
5   Klinik für Innere Medizin 4, Klinikum Nürnberg Süd, Nürnberg, Germany
,
Steffen Mühldorfer
6   Department of Gastroenterology, Klinikum Bayreuth, Bayreuth, Germany
,
Uwe Weickert
7   Department of Medicine II, SLK Kliniken Heilbronn, University of Heidelberg, Germany
,
Markus Laimer
8   Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin und Metabolismus, Universität Bern, Inselspital, Bern, Switzerland
,
Martin Pfeifer
9   Division of Diabetology, Klinik Tettnang, Germany
,
Lars Stechemesser
10   Department of Internal Medicine I, Paracelsus Medical University, Salzburg, Austria
,
ReinhardW. Holl
1   Institute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany
2   German Centre for Diabetes Research (DZD), Munich-Neuherberg, Germany
› Author Affiliations Funding This study was supported by the German Federal Ministry for Education and Research within the German Centre for Diabetes Research (DZD, 82DZD14A02). Further financial support was received by the German Robert Koch Institute (RKI) and the German Diabetes Association (DDG) Sponsors were not involved in data acquisition or analysis.
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Abstract

Aims To examine the association of frozen shoulder (FS) with demographic and diabetes-related outcomes in individuals with type 1 (T1D) or type 2 (T2D) diabetes aged ≥30 years.

Materials and methods Multivariable logistic regression models, adjusted for demographics were used to calculate the proportion of FS in association with age, gender, diabetes duration, body mass index (BMI), haemoglobin A1C (HbA1c) and diabetes treatment.

Results The unadjusted percentage of FS was higher in T1D compared to T2D (0.22% vs. 0.06%). In T1D, adjusted regression models revealed higher prevalence of FS in women than men (0.26 [0.20–0.34] % vs. 0.15 [0.11–0.21] %, p=0.010). No significant relationship of age and BMI with FS was found in both diabetes types. Longer diabetes duration was associated with a higher proportion of FS in T1D (p<0.001) and T2D (p=0.004). In T1D, HbA1c >7% was related to a higher proportion of FS compared to HbA1c ≤7% (0.25 [0.19–0.32] vs. 0.12 [0.08–0.20] %, p=0.007), while an inverse relationship was found in T2D (HbA1c ≤7%: 0.08 [0.07–0.10] vs. HbA1c >7%: 0.05 [0.04–0.06] %, p=0.001).

Conclusions Different associations of FS with gender and HbA1c were observed for T1D and T2D; however, longer diabetes duration increases the risk for FS independent of diabetes type. Musculoskeletal diseases are still underreported in individuals with diabetes and awareness should be raised for FS as a specific diabetes complication.

Key words

adhesive capsulitis - periarthritis humeroscapularis - PHS - haemoglobin A1c, body-mass-index

Supplementary Material



Publication History

Received: 12 April 2021
Received: 22 June 2021

Accepted: 29 June 2021

Article published online:
23 August 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
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