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DOI: 10.1055/a-1744-6697
Chronisch-entzündliche Darmerkrankungen in der COVID-Pandemie: Manifestationen und Management
Inflammatory bowel disease during the COVID-19 pandemic: manifestations and managementZusammenfassung
Die COVID-19-Pandemie beeinflusst das Leben von Patient*innen mit chronisch-entzündlichen Darmerkrankungen (CED) in erheblicher Weise. Betroffene und Angehörige haben zahlreiche Fragen zum Erkrankungsrisiko, zum Verlauf einer möglichen SARS-CoV-2-Infektion oder auch zum Einfluss der CED-spezifischen Therapie. Auch bestehen bei vielen CED-Patient*innen zusätzliche Fragen zu Sicherheit und Wirksamkeit einer Impfung gegen SARS-CoV-2. Ziel dieser Übersicht ist die Zusammenfassung der neusten Erkenntnisse zu COVID-19 und CED, aber auch die Diskussion zum Impfansprechen (humoral/zellulär), zum Einfluss laufender Therapie auf die Impfantwort sowie zur Häufigkeit von Nebenwirkungen und zur Bedeutung der Booster-Immunisierungen zu führen und für das Gespräch mit Patient*innen eine Evidenz-basierte Grundlage zu schaffen.
Abstract
The COVID-19 pandemic is significantly affecting the lives of patients with inflammatory bowel disease (IBD). Those affected and their relatives have numerous questions about the risk of the disease, the course of a possible SARS-CoV-2 infection or the influence of CED-specific therapy on these. Many IBD patients also have additional questions about the safety and effectiveness of a vaccination against SARS-CoV-2. The aim of this review is to summarize the latest findings on COVID-19 and IBD, but also to discuss vaccine response (humoral/cellular), the influence of ongoing therapy on the vaccine response as well as the frequency of side effects and the importance of booster immunizations and to create an evidence-based basis for discussion with patients.
Schlüsselwörter
SARS-CoV-2 - COVID-19 - chronisch entzündliche Darmerkrankungen - Morbus Crohn - Colitis ulcerosa - Immunsuppression - ImpfungKeywords
SARS-CoV-2 - COVID-19 - inflammatory bowel diseases - Crohn's disease - ulcerative colitis - immunosuppression - vaccinationPublication History
Received: 26 October 2021
Accepted after revision: 14 January 2022
Article published online:
11 February 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
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