Download PDF
Diabetologie und Stoffwechsel
DOI: 10.1055/a-2251-2772
DDG-Praxisempfehlung

Diabetes im Krankenhaus

Karsten Müssig
1   Klinik für Innere Medizin, Gastroenterologie und Diabetologie, Niels-Stensen-Kliniken, Franziskus-Hospital Harderberg, Georgsmarienhütte, Deutschland
,
Baptist Gallwitz
2   Department Innere Medizin, Abteilung IV – Diabetologie, Endokrinologie, Nephrologie, Universitätsklinikum Tübingen, Tübingen, Deutschland
,
Thomas Haak
3   Diabetes-Klinik am Diabetes Zentrum Mergentheim, Bad Mergentheim, Deutschland
,
Monika Kellerer
4   Zentrum für Innere Medizin I, Marienhospital Stuttgart, Stuttgart, Deutschland
,
Erhard Siegel
5   Klinik für Gastroenterologie, Diabetologie und Ernährungsmedizin, St. Josefskrankenhaus Heidelberg, Heidelberg, Deutschland
› Author Affiliations
› Further Information
Also available at
    Permissions and Reprints
Aktualisierungshinweis

Die DDG-Praxisempfehlungen werden regelmäßig zur zweiten Jahreshälfte aktualisiert. Bitte stellen Sie sicher, dass Sie jeweils die neueste Version lesen und zitieren.



Publication History

Article published online:
26 February 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Eckert AJ, Fritsche A, Icks A. et al. Common procedures and conditions leading to inpatient hospital admissions in adults with and without diabetes from 2015 to 2019 in Germany. Wien Klin Wochenschr 2023; 135: 325-335
    CrossrefPubMedGoogle Scholar
  • 2 Kufeldt J, Kovarova M, Adolph M. et al. Prevalence and Distribution of Diabetes Mellitus in a Maximum Care Hospital: Urgent Need for HbA1c-Screening. Exp Clin Endocrinol Diabetes 2018; 126: 123-129
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 ElSayed NA, Aleppo G, Aroda VR. et al. Diabetes Care in the Hospital: Standards of Care in Diabetes -2023. Diabetes Care 2023; 46: 267-278
    CrossrefPubMedGoogle Scholar
  • 4 Brunkhorst FM, Engel C, Bloos F. et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008; 358: 125-139
    CrossrefPubMedGoogle Scholar
  • 5 Finfer S, Chittock DR, Su SY. NICE-SUGAR Study Investigators. et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009; 360: 1283-1297
    CrossrefPubMedGoogle Scholar
  • 6 Chang S, Xu M, Wang Y. et al. Acute Glycemic Variability and Early Outcomes After Cardiac Surgery: A Meta-Analysis. Horm Metab Res 2023; 55: 771-780
    Article in Thieme ConnectPubMedGoogle Scholar
  • 7 Barmanray RD, Cheuk N, Fourlanos S. In-hospital hyperglycemia but not diabetes mellitus alone is associated with increased in-hospital mortality in community-acquired pneumonia (CAP): a systematic review and meta-analysis of observational studies prior to COVID-19. BMJ Open Diabetes Res Care 2022; 10: e002880
    CrossrefPubMedGoogle Scholar
  • 8 Dungan KM, Braithwaite SS, Preiser JC. Stress hyperglycaemia. Lancet 2009; 373: 1798-1807
    CrossrefPubMedGoogle Scholar
  • 9 Li L, Zhao M, Zhang Z. et al. Prognostic significance of the stress hyperglycemia ratio in critically ill patients. Cardiovasc Diabetol 2023; 22: 275-284
    CrossrefPubMedGoogle Scholar
  • 10 Mader JK, Brix JM, Aberer F. et al. Diabetesmanagement im Krankenhaus (Update 2023) [Hospital diabetes management (Update 2023)]. Wien Klin Wochenschr 2023; 135 (Suppl. 01) 242-255
    CrossrefPubMedGoogle Scholar
  • 11 Kietaibl AT, Huber J, Clodi M. et al. Positionspapier:Operation und Diabetes mellitus. Wien Klin Wochenschr 2023; 135 (Suppl. 01) 256-271
    CrossrefPubMedGoogle Scholar
  • 12 Zhang Y, Zheng QJ, Wang S. et al. Diabetes mellitus is associated with increased risk of surgical site infections: a meta-analysis of prospective cohort studies. Am J Infect Control 2015; 43: 810-815
    CrossrefPubMedGoogle Scholar
  • 13 Martin ET, Kaye KS, Knott C. et al. Diabetes and risk of surgical site infection: a systematic review and meta-analysis. Infect Control Hosp Epidemiol 2016; 37: 88-99
    CrossrefPubMedGoogle Scholar
  • 14 Tao X, Matur AV, Palmisciano P. Preoperative HbA1c and Postoperative Outcomes in Spine Surgery: A Systematic Review and Meta-Analysis. Spine (Phila Pa 1976) 2023; 48: 1155-1165
    CrossrefPubMedGoogle Scholar
  • 15 ElSayed NA, Aleppo G, Aroda VR. et al. 6. Glycemic Targets: Standards of Care in Diabetes-2023. Diabetes Care 2023; 46 (Suppl. 01) S97-S110
    CrossrefPubMedGoogle Scholar
  • 16 Lipska KJ, Hirsch IB, Riddle MC. Human Insulin for Type 2 Diabetes: An Effective, Less-Expensive Option. JAMA 2017; 318: 23-24
    CrossrefPubMedGoogle Scholar
  • 17 Baker M, Musselman ME, Rogers R. et al. Practical implementation of remote continuous glucose monitoring in hospitalized patients with diabetes. Am J Health Syst Pharm 2022; 79: 452-458
    CrossrefPubMedGoogle Scholar
  • 18 Davies MJ, Aroda VR, Collins BS. et al. Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2022; 45: 2753-2786
    CrossrefPubMedGoogle Scholar
  • 19 Galindo RJ, Aleppo G, Klonoff DC. et al. Implementation of Continuous Glucose Monitoring in the Hospital: Emergent Considerations for Remote Glucose Monitoring During the COVID-19 Pandemic. J Diabetes Sci Technol 2020; 14: 822-832
    CrossrefPubMedGoogle Scholar
  • 20 Longo RR, Elias H, Khan M. et al. Use and Accuracy of Inpatient CGM During the COVID-19 Pandemic: An Observational Study of General Medicine and ICU Patients. J Diabetes Sci Technol 2022; 16: 1136-1143
    CrossrefPubMedGoogle Scholar
  • 21 Wright JJ, Williams AJ, Friedman SB. et al. Accuracy of Continuous Glucose Monitors for Inpatient Diabetes Management. J Diabetes Sci Technol 2022; DOI: 10.1177/19322968221076562.
    CrossrefPubMedGoogle Scholar
  • 22 Stacul F, van der Molen AJ, Reimer P. et al. Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 2011; 2: 2527-2541
    CrossrefPubMedGoogle Scholar
  • 23 Deutsche Diabetesgesellschaft. Positionspapier der Deutschen Diabetes Gesellschaft zur Therapie des Diabetes mellitus im Krankenhaus. 2018 Im Internet (Stand: 01.09.2023): https://www.ddg.info/politik/stellungnahmen/krankenhaus
    PubMedGoogle Scholar
  • 24 Perkovic V, Agarwal R, Fioretto P. et al. Management of patients with diabetes and CKD: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference. Kidney Int 2016; 90: 1175-1183
    CrossrefPubMedGoogle Scholar
  • 25 Lalau JD, Kajbaf F, Protti A. et al. Metformin-associated lactic acidosis (MALA): Moving towards a new paradigm. Diabetes Obes Metab 2017; 19: 1502-1512
    CrossrefPubMedGoogle Scholar
  • 26 Frisch A, Chandra P, Smiley D. et al. Prevalence and clinical outcome of hyperglycemia in the perioperative period in noncardiac surgery. Diabetes Care 2010; 33: 1783-1788
    CrossrefPubMedGoogle Scholar
  • 27 Deusenberry CM, Coley KC, Korytkowski MT. et al. Hypoglycemia in hospitalized patients treated with sulfonylureas. Pharmacotherapy 2012; 32: 613-617
    CrossrefPubMedGoogle Scholar
  • 28 Zinman B, Wanner C, Lachin JM. et al. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med 2015; 373: 2117-2128
    CrossrefPubMedGoogle Scholar
  • 29 Umpierrez G, Korytkowski M. Diabetic emergencies – ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia. Nat Rev Endocrinol 2016; 12: 222-232
    CrossrefPubMedGoogle Scholar
  • 30 Landgraf R, Aberle J, Birkenfeld AL. et al. Therapy of Type 2 Diabetes. Exp Clin Endocrinol Diabetes 2022; 130 (Suppl. 01) S80-S112
    Article in Thieme ConnectPubMedGoogle Scholar
  • 31 Marso SP, Daniels GH, Brown-Frandsen K. et al. Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med 2016; 375: 311-322
    CrossrefPubMedGoogle Scholar
  • 32 Haak T, Gölz S, Fritsche A. et al. Therapie des Typ-1-Diabetes. Kurzfassung der S3-Leitlinie (AWMF-Registernummer: 057-013; 2. Auflage). Diabetol Stoffwechs 2023; 18 (Suppl. 02) S136-S147
    Article in Thieme ConnectGoogle Scholar
  • 33 Diabetes Canada Clinical Practice Guidelines Expert Committee. Goguen J, Gilbert J. Hyperglycemic Emergencies in Adults. Can J Diabetes 2018; 42: S109-S114
    CrossrefPubMedGoogle Scholar
  • 34 Kitabchi AE, Umpierrez GE, Miles JM. et al. Hyperglycemic crises in adult patients with diabetes. Diabetes Care 2009; 32: 1335-1343
    CrossrefPubMedGoogle Scholar
  • 35 Nyenwe EA, Kitabchi AE. Evidence-based management of hyperglycemic emergencies in diabetes mellitus. Diabetes Res Clin Pract 2011; 94: 340-351
    CrossrefPubMedGoogle Scholar
  • 36 Joint British Diabetes Societies for inpatient care. The management of the hyperosmolar hyperglycaemic state (HHS) in adults with diabetes: August 2012. 2012 Im Internet (Stand: 13.02.2024): http://www.diabetologists-abcd.org.uk/JBDS/JBDS_IP_HHS_Adults.pdf
    PubMedGoogle Scholar
  • 37 Galway U, Chahar P, Schmidt MT. et al. Perioperative challenges in management of diabetic patients undergoing non-cardiac surgery. World J Diabetes 2021; 12: 1255-1266
    CrossrefPubMedGoogle Scholar
  • 38 Tao LS, Mackenzie CR, Charlson ME. Predictors of postoperative complications in the patient with diabetes mellitus. J Diabetes Complications 2008; 22: 24-28
    CrossrefPubMedGoogle Scholar
  • 39 Gallwitz B. Diabetes im Krankenhaus: Perioperative Einstellung der Patienten. Dtsch Arztebl 2019; 116 (04) DOI: 10.3238/PersDia.2019.05.17.01.
    CrossrefGoogle Scholar
  • 40 Halkos ME, Lattouf OM, Puskas JD. et al. Elevated preoperative hemoglobin A1c level is associated with reduced long-term survival after coronary artery bypass surgery. Ann Thorac Surg 2008; 86: 1431-1437
    CrossrefPubMedGoogle Scholar
  • 41 Dronge AS, Perkal MF, Kancir S. et al. Long-term glycemic control and postoperative infectious complications. Arch Surg 2006; 141: 375-380
    CrossrefPubMedGoogle Scholar
  • 42 Buchleitner AM, Martínez-Alonso M, Hernández M. et al. Perioperative glycaemic control for diabetic patients undergoing surgery. Cochrane Database Syst Rev 2012; 9: CD007315
    Google Scholar
  • 43 Mahmood S, Farooqui SM, Madhoun MF. Predictors of inadequate bowel preparation for colonoscopy: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol 2018; 30: 819-826
    CrossrefPubMedGoogle Scholar
  • 44 Piper MS, Saad RJ. Diabetes Mellitus and the Colon. Curr Treat Options Gastroenterol 2017; 15: 460-474
    CrossrefPubMedGoogle Scholar
  • 45 Johnson DA, Barkun AN, Cohen LB. et al. Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US multi-society task force on colorectal cancer. Gastroenterology 2014; 147: 903-924
    CrossrefPubMedGoogle Scholar
  • 46 Adamek HE, Bergmann L, Müssig K. Koloskopievorbereitung bei Patienten mit Diabetes mellitus: Entwicklung einer Handlungsempfehlung. Z Gastroenterol 2022; 60: 784-789
    Article in Thieme ConnectPubMedGoogle Scholar
  • 47 Lewandowski K, Rydzewska G, Ledwoń TK. Preparation for endoscopic examinations in patients with diabetes and hypoglycaemia. Prz Gastroenterol 2021; 16: 297-305
    PubMedGoogle Scholar
  • 48 Müssig K, Adamek HE. Adjustment of Anti-Hyperglycaemic Agents During Bowel Preparation for Colonoscopy in Patients with Diabetes. Exp Clin Endocrinol Diabetes 2022; 130: 627-632
    Article in Thieme ConnectPubMedGoogle Scholar
  • 49 Hochberg I, Segol O, Shental R. et al. Antihyperglycemic therapy during colonoscopy preparation: A review and suggestions for practical recommendations. United European Gastroenterol J 2019; 7: 735-740
    CrossrefPubMedGoogle Scholar
  • 50 Australian Diabetes Society. Alert update September 2020. Periprocedural Diabetic Ketoacidosis (DKA) with SGLT2 Inhibitor Use. Im Internet (Stand: 13.02.2024): https://diabetessociety.com.au/downloads/20201015%20ADS_DKA_SGLT2i_Alert_update_Sept_2020.pdf
    Google Scholar
  • 51 Australian Diabetes Society. Peri-operative diabetes management guidelines. Im Internet (Stand: 13.02.2024): https://diabetessociety.com.au/documents/PerioperativeDiabetesManagementGuidelinesFINALCleanJuly2012.pdf
    Google Scholar
  • 52 van Raalte DH, Diamant M. Steroid diabetes: from mechanism to treatment?. Neth J Med 2014; 72: 62-72
    PubMedGoogle Scholar
  • 53 Tamez-Pérez HE, Quintanilla-Flores DL, Rodríguez-Gutiérrez R. et al. Steroid hyperglycemia: Prevalence, early detection and therapeutic recommendations: A narrative review. World J Diabetes 2015; 6: 1073-1081
    CrossrefPubMedGoogle Scholar
  • 54 Katsuyama T, Sada KE, Namba S. et al. Risk factors for the development of glucocorticoid-induced diabetes mellitus. Diabetes Res Clin Pract 2015; 108: 273-279
    CrossrefPubMedGoogle Scholar
  • 55 Stauber MN, Aberer F, Oulhaj A. et al. Early Hyperglycemia after Initiation of Glucocorticoid Therapy Predicts Adverse Outcome in Patients with Acute Graft-versus-Host Disease. Biol Blood Marrow Transplant 2017; 23: 1186-1192
    CrossrefPubMedGoogle Scholar
  • 56 Hjelmesaeth J, Hartmann A, Leivestad T. et al. The impact of early-diagnosed new-onset post-transplantation diabetes mellitus on survival and major cardiac events. Kidney Int 2006; 69: 588-595
    CrossrefPubMedGoogle Scholar
  • 57 Clore JN, Thurby-Hay L. Glucocorticoid-induced hyperglycemia. Endocr Pract 2009; 15: 469-474
    CrossrefPubMedGoogle Scholar
  • 58 Gosmanov AR, Umpierrez GE. Management of hyperglycemia during enteral and parenteral nutrition therapy. Curr Diab Rep 2013; 13: 155-162
    CrossrefPubMedGoogle Scholar
  • 59 Clubbs Coldron B, Coates V, Khamis A. et al. Use of continuous glucose monitoring in non-ICU hospital settings for people with diabetes: a scoping review of emerging benefits and issues. J Diabetes Sci Technol 2023; 17: 467-473
    CrossrefPubMedGoogle Scholar
  • 60 Korytkowski MT, Muniyappa R, Antinori-Lent K. et al. Management of hyperglycemia in hospitalized adult patients in non-critical care settings: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2022; 107: 2101-2128
    CrossrefPubMedGoogle Scholar
  • 61 Dillmann C, Amoura L, Fall Mostaine F. et al. Feasibility of real-time continuous glucose monitoring telemetry system in an inpatient diabetes unit: a pilot study. J Diabetes Sci Technol 2022; 16: 955-961
    CrossrefPubMedGoogle Scholar
  • 62 Ehrhardt N, Hirsch IB. The impact of COVID-19 on CGM use in the hospital. Diabetes Care 2020; 43: 2628-2630
    CrossrefPubMedGoogle Scholar
  • 63 Avari P, Lumb A, Flanagan D. et al. Continuous Glucose Monitoring Within Hospital: A Scoping Review and Summary of Guidelines From the Joint British Diabetes Societies for Inpatient Care. J Diabetes Sci Technol 2023; 17: 611-624
    CrossrefPubMedGoogle Scholar
  • 64 Wallia A, Umpierrez GE, Rushakoff RJ. et al. Consensus statement on inpatient use of continuous glucose monitoring. J Diabetes Sci Technol 2017; 11: 1036-1044
    CrossrefPubMedGoogle Scholar
  • 65 Inoue S, Egi M, Kotani J. et al. Accuracy of blood-glucose measurements using glucose meters and arterial blood gas analyzers in critically ill adult patients: systematic review. Crit Care 2013; 17: R48
    CrossrefPubMedGoogle Scholar
  • 66 Galindo RJ, Umpierrez GE, Rushakoff RJ. et al. Continuous glucose monitors and automated insulin dosing systems in the hospital consensus guideline. J Diabetes Sci Technol 2020; 14: 1035-1064
    CrossrefPubMedGoogle Scholar
  • 67 Flanagan D, Dhatariya K, Kilvert A. Joint British Diabetes Societies (JBDS) for Inpatient Care group and Guidelines writing group. Self-management of diabetes in hospital: a guideline from the Joint British Diabetes Societies (JBDS) for Inpatient Care group. Diabet Med 2018; 35: 992-996
    CrossrefPubMedGoogle Scholar
  • 68 Kannan S, Satra A, Calogeras E. et al. Insulin pump patient characteristics and glucose control in the hospitalized setting. J Diabetes Sci Technol 2014; 8: 473-478
    CrossrefPubMedGoogle Scholar
  • 69 Cook CB, Beer KA, Seifert KM. et al. Transitioning insulin pump therapy from the outpatient to the inpatient setting: a review of 6 years’ experience with 253 cases. J Diabetes Sci Technol 2012; 6: 995-1002
    CrossrefPubMedGoogle Scholar
  • 70 Noschese ML, DiNardo MM, Donihi AC. et al. Patient outcomes after implementation of a protocol for inpatient insulin pump therapy. Endocr Pract 2009; 15: 415-424
    CrossrefPubMedGoogle Scholar
  • 71 Avari P, Lumb A, Flanagan D. et al. Insulin Pumps and Hybrid Close Loop Systems Within Hospital: A Scoping Review and Practical Guidance From the Joint British Diabetes Societies for Inpatient Care. J Diabetes Sci Technol 2023; 17: 625-634
    CrossrefPubMedGoogle Scholar
  • 72 Dashora U, Levy N, Dhatariya K. et al. Managing hyperglycaemia during antenatal steroid administration, labour and birth in pregnant women with diabetes-an updated guideline from the Joint British Diabetes Society for Inpatient Care. Diabet Med 2022; 39: e14744
    CrossrefPubMedGoogle Scholar
  • 73 Yeh T, Yeung M, Mendelsohn Curanaj FA. Managing patients with insulin pumps and continuous glucose monitors in the hospital: to wear or not to wear. Curr Diab Rep 2021; 21: 7
    CrossrefPubMedGoogle Scholar
  • 74 Bally L, Thabit H, Hartnell S. et al. Closed-loop insulin delivery for glycemic control in noncritical care. N Engl J Med 2018; 379: 547-556
    CrossrefPubMedGoogle Scholar
  • 75 Atif Z, Halstrom A, Peragallo-Dittko V. et al. Efficacy of hybrid closed-loop insulin delivery system in a hospital setting: a case series. AACE Clin Case Rep 2021; 7: 184-188
    CrossrefPubMedGoogle Scholar