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Horm Metab Res 1976; 8(3): 217-220
DOI: 10.1055/s-0028-1093644
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© Georg Thieme Verlag KG Stuttgart · New York

Comparative Study of Plasma Cortisol Evolution in TRH or Placebo Injected Patients With of Without Thyroid Disease

J.  Ducobu , N.  Demeester-Mirkine , A.  Bossuyt , H.  Braumann , J.  Corvilain
  • Department of Internal Medicine and Laboratory of Biological Chemistry, Brugmann Hospital, Brussels University, Brussels, Belgium
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Publication Date:
23 December 2008 (online)

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Abstract

The plasma Cortisol evolution under TRH has been compared in 27 euthyroid, 12 hyperthyroid and 5 patients with hot nodules and in 15 control individuals receiving a placebo or sham injection. The results showed no statistical difference in plasma cortisol evolution between the groups, suggesting no influence of the thyroid status or TSH secretion on the spontaneous fall of cortisol level during the time of the test.

Key words

Cortisolemia - TRH-Stimulation - Placebo - Sham Injection - Euthyroid - Hyperthyroid - Hot Nodules

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