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Exp Clin Endocrinol Diabetes 1988; 91(1): 105-108
DOI: 10.1055/s-0029-1210729
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effects of Bovine Growth Hormone in Infant Rats from Reduced Litters

A. Ryníková, J. Koppel, S. Kuchár, Š. Mozeš, P. Noskovič, K. Boďa
  • Institute of Animal Physiology (Head: Academician K. Boďa) Slovak Academy of Sciences, Košice/Czechoslovakia
Further Information

Publication History

1987

Publication Date:
16 July 2009 (online)

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Summary

The objective of this study was to determine the effects of growth hormone on body growth and the content of RNA, DNA and protein in liver, brain and heart muscle in rat pups from reduced nests. Suckling rats raised in litters of 4 youngs were daily injected from 3rd to 28th day of life with 1 µg of bGH/g body weight. Our results show that GH administration evoked higher body weight gain and increase of tail length after 23rd day of life. There was significant increase of liver content of nucleic acids and protein. This GH-responsivity of pups from reduced nests might be related to differences in their metabolic profile and accelerated somatic and psychosocial development in comparison to normal youngs.

Key words

GH - rat pups - body growth

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