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Exp Clin Endocrinol Diabetes 1990; 95(3): 369-373
DOI: 10.1055/s-0029-1210978
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Simultaneous Occurrence of Diabetes Insipidus and Ascites due to Liver Cirrhosis : Clinical and Pathophysiological Studies

J. P. Radó, A. Taller
  • Department of Medicine (Head : János P. Radó), Emil Weil Hospital, Budapest/Hungary
Further Information

Publication History

1989

Publication Date:
16 July 2009 (online)

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Summary

Authors describe the simultaneous occurrence of ascites due to liver cirrhosis and diabetes insipidus in a patient with consistently normal urine volume. The diagnosis of diabetes insipidus has been proved by the water deprivation test combined with the administration of dDAVP as well as by serial determinations of plasma arginine vasopressin levels before and during infusion of hypertonic sodium chloride solution. Authors discuss the differential-diagnostic difficulties of the case and consider the mechanisms playing a role in the abolishment of diabetic polyuria by hepatic disease.

Key words

Diabetes insipidus - Liver cirrhosis - dDAVP - Antidiuresis plasma vasopressin

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