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Thorac Cardiovasc Surg 2012; 60(08): 525-532
DOI: 10.1055/s-0031-1293603
Original Thoracic
Georg Thieme Verlag KG Stuttgart · New York

Clinical Outcomes and Prognostic Factors for Surgically Resected Second Primary Lung Cancer

Mi Kyung Bae
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
,
Chun Sung Byun
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
,
Chang Young Lee
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
,
Jin Gu Lee
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
,
In Kyu Park
2   Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
,
Dae Joon Kim
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
,
Kyung Young Chung
1   Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea
› Author Affiliations
Further Information

Publication History

30 April 2011

08 June 2011

Publication Date:
12 March 2012 (online)

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Abstract

Background This study was designed to analyze the predictive factors for survival in second primary lung cancer patients following operation.

Methods A total of 1852 patients who underwent resection for primary lung cancer between January 1990 and December 2008 were reviewed, retrospectively.

Results Nineteen patients were treated for synchronous second primary lung cancer and 23 patients were treated for metachronous cancer. The overall 5-year survival rate for patients with synchronous second primary lung cancer was comparable to that of patients with single-lung cancer (51.4 vs. 48.7%, p = 0.755). The overall 5-year survival rate after the first tumor resection in patients with metachronous second primary lung cancer was significantly better than that of patients with single-lung cancer (85.4 vs. 48.7%, p = 0.003), but was not significantly different after the second tumor resection (77.0 vs. 48.7%, p = 0.057).

Conclusion Surgically resected second primary lung cancer had a survival comparable with single-lung cancer. Histologic concordance between the first and second tumors, and the pathological stage were important prognostic factors in second primary lung cancer.

Keywords

lung cancer treatment (surgery medical) - surgery - complications - outcomes (includes mortality morbidity)
 

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