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Semin Thromb Hemost 2012; 38(03): 265-267
DOI: 10.1055/s-0032-1309286
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

FEIBA: A Prohemostatic Agent

Caroline Cromwell
1   Division of Hematology/Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, New York
,
Louis M. Aledort
1   Division of Hematology/Oncology, Department of Medicine, Mount Sinai School of Medicine, New York, New York
› Author Affiliations
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Publication History

Publication Date:
29 March 2012 (online)

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Abstract

Factor eight inhibitor bypassing activity (FEIBA), Anti-Inhibitor Coagulation Complex has been used for over 30 years in hemophiliac patients with inhibitors. The history of its use is reviewed here, including issues related to thrombosis, efficacy, and comparison to alternative bypassing agents. The need for surrogate assays to monitor effective hemostasis with the use of FEIBA remains.

Keywords

inhibitors - hemophilia - factor eight inhibitor bypassing activity - thrombosis
 

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