Nuklearmedizin 1976; 15(02): 60-62
DOI: 10.1055/s-0038-1624934
Originalarbeiten — Original Articles
Schattauer GmbH

Scintiscan Characteristics of Normal Thyroid Gland in a Region of Known Iodine Intake

Szintigraphische Charakteristiken der normalen Schilddrüse in einem Gebiet mit bekannter Jodzufuhr
G. T. Krishnamurthy*
1   Nuclear Medicine and Research Services, Veterans Administration Wadsworth Hospital Center, Los Angeles; Department of Medicine, University of California at Los Angeles (UCLA) School of Medicine
,
Lucille E. Snoop**
1   Nuclear Medicine and Research Services, Veterans Administration Wadsworth Hospital Center, Los Angeles; Department of Medicine, University of California at Los Angeles (UCLA) School of Medicine
› Author Affiliations
Further Information

Publication History

Received:19 July 1975

Publication Date:
11 January 2018 (online)

Summary

Morphological features of a normal thyroid gland in a geographical region where the daily iodine intake is about 1 mg are established. The mean weight of the thyroid gland is 31.3 gm with a range from 19 to 43 gm. Oblique length of the right lobe is 5.0 cm and that of the left lobe 4.8 cm. The surface area of the right and left lobes is 9.7 and 9.1 cm2, respectively. The weight of the thyroid gland calculated on the basis of the scan obtained with 99mTcO4 is quite variable and shows poor correlation (γ = 0.40) with the weight obtained on the basis of I-131 scan. It is suggested that the criteria of normalcy be established regionally based on iodine intake, and that an isotope of iodine be used in calculating the weight of thyroid gland for dosimetry purposes.

Die morphologischen Gegebenheiten der normalen Schilddrüse in einem geographischen Gebiet mit täglicher Jodzufuhr von 1 mg wird dargestellt. Das mittlere Schilddrüsengewicht betrug 31,3 g mit einer Schwankung von 19—43 g. Der schräge Längsdurchmesser des rechten Lappens ist 5,0 cm, die des linken 4,8 cm. Die Oberfläche des rechten und des linken Lappens ist 9,7 bzw. 9,1 cm2. Das Schilddrüsengewicht, das auf Grundlage einer 99mTcO4-Szintigraphie berechnet wurde, ist unterschiedlich und zeigt eine schlechte Korrelation (a = 0,40) mit dem Gewicht, das aus einem 131J-Scan berechnet wurde. Es wird vorgeschlagen, daß die Kriterien des Normalen für eine Gegend festgelegt werden auf der Basis der Jodzufuhr und daß ein Jodisotop verwendet wird, um das Schilddrüsengewicht für dosimetrische Zwecke zu bestimmen.

* G.T. Krishnamurthy, M. B. B. S., M.S., F. A. C. P., Staff Physician, Nuclear Medicine Service, VA Wadsworth Hospital Center; and Assistant Professor of Medicine, UCLA School of Medicine.


** Lucille E. Shoop, R. N., Nuclear Medicine Service, VA Wadsworth Hospital Center, Los Angeles.


 
  • References

  • 1 Pittman J. A, Daily G. E, Beselin R. J. Changing mal values for thyroidal radioiodine uptake. New Engl. J. Med 1969; 280: 1431-1434.
  • 2 Nelson J. E. Effect of increased iodine intake on the thyroidal response to TSH stimulation. J. Nucl. Med 1972; 13: 828-833.
  • 3 Allen H. C, Goodwin W. E. The scintillation counter as an instrument for the in vivo determination of thyroid weight. Radiology 1952; 58: 68-69.
  • 4 Goodwin W. E, Cassen B, Bauer F. K. Thyroid gland weight determination from thyroid scintigram with postmortem verification. Radiology 1953; 61: 88-92.
  • 5 Tong E. D. K, Rubenfeld S. Scan measurement of normal and enlarged thyroid gland. Amer. J. Roentgenol 1972; 115: 706-708.
  • 6 Andros G, Harper P. L, Lathoop K. A. et al Pertechnetate-99m localization in man with applications to thyroid scanning and the study of thyroid physiology. J. Clin. Endocr 1965; 25: 1067.
  • 7 Degrossi Q, Golta H, Olivari A. et al Possibilities of using Tc-99m in place of radioiodine in thyroid function studies. Nucl. Med 1965; 4: 383-390.
  • 8 Atkins H. L, Richards P. Assessment of thyroid function and anatomy with technetium-99m pertechnetate. J. Nucl. Med 1968; 9: 7-15.
  • 9 Dodd W. J, Powell M. Thyroid scanning with technetium-99m pertechnetate. Radiology 1968; 9: 27-31.
  • 10 Cherkes N. D. Choice of isotope for thyroid scanning. Letters to the editor. J. Nucl. Med 1966; 9: 504-505.
  • 11 Usher M. S, Arzoumenian A. Y. Thyroid nodule scan made with pertechnetate and iodine may given inconsistent result. J. Nucl. Med 1971; 12: 136-137.
  • 12 Steinberg M, Cavelein R. R, Choy S. H. Uptake of technetium-99m pertechnetate in a primary thyroid carcinoma: Need for caution in evaluating nodules. J. Clin. Endocr 1970; 31: 81-84.
  • 13 Meighon J. W, Dwarkin H. J. Failure to detect I-131 positive thyroid metastasis with 99mTc. J. Nucl. Med 1970; 11: 173-174.
  • 14 Krishnamurthy G. T, Shoop L, Walsh C. F. et al Comparison of 99m-technetium pertechnetate and radioiodine (I-131) as thyroid scanning agents. Nucl.-Med 1973; 12: 97-106.