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Thromb Haemost 1971; 25(02): 312-315
DOI: 10.1055/s-0038-1654305
Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH

Additional Evidence for the Existence of a Precursor Molecule of the Prothrombin Complex in Oral Anticoagulation

J. J Veltkamp
,
H Muis
,
A. D Muller
,
H. C Hemker
,
E. A Loeliger
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Publikationsdatum:
28. Juni 2018 (online)

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Summary

By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.

 

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