Geburtshilfe Frauenheilkd 2016; 76(03): 228-230
DOI: 10.1055/s-0042-103565
Aktuell diskutiert
Georg Thieme Verlag KG Stuttgart · New York

Geburtshilfe – Zusammenhang zwischen mütterlichem Body-Mass-Index und fetalen Fehlbildungen

Christel Eckmann-Scholz
Further Information

Publication History

Publication Date:
07 April 2016 (online)

In der Bundesrepublik Deutschland waren im Jahr 2009 laut statistischem Bundesamt 51,4% der Bevölkerung über 18 Jahre übergewichtig. Ein Trend, der sich weltweit fortsetzt: 2008 waren nach einer Schätzung der Weltgesundheitsorganisation 1,4 Milliarden Menschen übergewichtig. Davon waren 0,2 Milliarden Männer und 0,3 Milliarden Frauen adipös (World Health Organization 2014). Diese Problematik ist auch für die Betreuung der Patientinnen in der Schwangerschaft nicht unerheblich.

 
  • Literatur

  • 1 Edlow AG, Vora NL, Hui L et al. Maternal obesity affects fetal neurodevelopmental and metabolic gene expression: A pilot study. PLoS ONE 2014; 9: e88661 DOI: 10.1371/journal.pone.0088661.
  • 2 Meenakshi Srivastava R, Sharma NR. et al. Obstetric behavior and pregnancy outcome in overweight and obese women: maternal and fetal complications and risks in relation to maternal overweight and obesity. J Obstet Gynaecol India 2012; 62: 276-280
  • 3 Usha Kiran TS, Hemmadi S, Bethel J et al. Outcome of pregnancy in a woman with an increased body mass index. BJOG 2005; 112: 768-772
  • 4 Heslehurst N, Simpson H, Ells LJ et al. The impact of maternal BMI status on pregnancy outcomes with immediate short-term obstetric resource implications: a meta-analysis. Obes Rev 2008; 9: 635-683
  • 5 Boney CM, Verma A, Tucker R et al. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 2005; 115: e290-6
  • 6 Rasmussen SA, Chu SY, Kim SY et al. Maternal obesity and risk of neural tube defects: a metaanalysis. Am J Obstet Gynecol 2008; 198: 611-619
  • 7 Stothard KJ, Tennant Peter WG, Bell R et al. Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis. JAMA 2009; 301: 636-650
  • 8 Mills JL, Troendle J, Conley MR et al. Maternal obesity and congenital heart defects: a population-based study. Am J Clin Nutr 2010; 91: 1543-1549
  • 9 Gilboa SM, Correa A, Botto LD et al. Association between prepregnancy body mass index and congenital heart defects. Am J Obstet Gynecol 2010; 202: 51.e1-51.e10
  • 10 Dennedy MC, Avalos G, OʼReilly MW et al. ATLANTIC-DIP: raised maternal body mass index (BMI) adversely affects maternal and fetal outcomes in glucose-tolerant women according to International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. J Clin Endocrinol Metab 2012; 97: E608-12
  • 11 Aagaard-Tillery KM, Flint Porter T, Malone FD et al. Influence of maternal BMI on genetic sonography in the FaSTER trial. Prenat Diagn 2010; 30: 14-22
  • 12 Best KE, Tennant PWG, Bell R et al. Impact of maternal body mass index on the antenatal detection of congenital anomalies. BJOG 2012; 119: 1503-1511
  • 13 Waller DK, Shaw GM, Rasmussen SA et al. Prepregnancy obesity as a risk factor for structural birth defects. Arch Pediatr Adolesc Med 2007; 161: 745-750
  • 14 Eckmann-Scholz C, Hoffmann U, Kramer HH et al. Perinatal management of pregnancies with severe fetal heart defects and epigenetic aspects. J Matern Fetal Neonatal Med 2012; 25: 2542-2545
  • 15 Cai GJ, Sun XX, Zhang L et al. Association between maternal body mass index and congenital heart defects in offspring: a systematic review. Am J Obstet Gynecol 2014; 211: 91-117