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Cent Eur Neurosurg 2006; 67(4): 210-212
DOI: 10.1055/s-2006-933536
Case Report

© Georg Thieme Verlag Stuttgart · New York

Nontraumatic Spinal Epidural Hematoma Associated with Clopidogrel

Nicht-traumatisches spinales Epiduralhämatom unter ClopidogrelK. Karabatsou1 , A. Sinha1 , K. Das2 , N. G. Rainov3 , 4
  • 1Department of Neurosurgery, The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, United Kingdom
  • 2Department of Neuroradiology, The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, United Kingdom
  • 3Department of Neurosurgery, Central Clinic Augsburg, Augsburg, Germany
  • 4Department of Neurosurgery, Martin-Luther-University Halle-Wittenberg, Halle, Germany
Further Information

Publication History

Publication Date:
14 November 2006 (online)

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Abstract

A 73-year-old female treated with clopidogrel for vascular disease presented with sudden onset of back pain, urinary retention and paraplegia. MRI scans demonstrated a thoracolumbar epidural hematoma and the patient underwent emergency laminectomy for evacuation of the hematoma. A possible causal link between clopidogrel and occurrence of the hemorrhage is discussed and the literature on spontaneous spinal hematomas is reviewed.

Zusammenfassung

Diese 73-jährige Frau, die wegen einer Gefäßerkrankung mit Clopidogrel behandelt wurde, stellte sich mit plötzlich auftretendem Rückenschmerz, Harnverhalt und Paraplegie der Beine vor. MRT-Aufnahmen zeigten ein thorakolumbales Epiduralhämatom, das über eine Laminektomie dringend ausgeräumt wurde. Eine kausale Beziehung zwischen der Einnahme von Clopidogrel und dem Auftreten des spinalen Epiduralhämatoms wird im Kontext der Literatur diskutiert.

Key words

clopidogrel - epidural - hematoma - spinal

Schlüsselwörter

Clopidogrel - epidural - Hämatom - spinal

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MD DSc FRCSEd N. G. Rainov

Department of Neurosurgery · Central Clinic Augsburg

Stenglinstr. 2

86156 Augsburg

Germany

Phone: +49/8 21/4 00 22 51

Fax: +49/8 21/4 00 33 14

Email: nikolai.rainov@medizin.uni-halle.de

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