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Horm Metab Res 1991; 23(10): 473-475
DOI: 10.1055/s-2007-1003732
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© Georg Thieme Verlag, Stuttgart · New York

Failure to Demonstrate Natriuretic Activity in the Posterior Pituitary After Immunoneutralization of the Vasopressin Content

J. Ponec, O. Földes, B. Lichardus
  • Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Czechoslovakia
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Publication History

1990

1991

Publication Date:
14 March 2008 (online)

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Summary

The attempt to demonstrate the presence of a natriuretic substance in the posterior pituitary after immunoneutralization of the AVP content failed. Rats infused i. v. AVP-immunoneutralized posterior pituitary extract did not respond by natriuresis to a saline infusion, in contrast to those infused untreated posterior pituitary extract. Thus, vasopressin seems to be the natriuretic substance in the posterior pituitary extract.

Key words

Posterior Pituitary - Vasopressin - Natriuresis

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