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Horm Metab Res 1986; 18(10): 693-697
DOI: 10.1055/s-2007-1012409
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Adrenergic Control of Lipolysis and Metabolic Responses in Obesity

B. Zahorska-Markiewicz, C. Kucio, D. Piskorska
  • Department of Gastroenterology and Biochemistry, Silesian School of Medicine, Katowice, Poland
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Publication History

1985

1985

Publication Date:
14 March 2008 (online)

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Summary

Adrenergic modulation of lipolysis was determined in obese and lean women. Epinephrine was infused alone, or in combination with propranolol, or with phentolamine. In both obese and lean subjects slight α- and prevalent β-adrenergic lipolytic responsiveness was observed.

α-adrenergic blockade by yohimbine potentiated lipolysis and exercise energy expenditure. Yohimbine application during the slimming treatment increased weight loss without side effects.

Key-Words

Obesity - Lipolysis - Energy Expenditure - Adrenergic Modulation

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