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Horm Metab Res 1985; 17(5): 241-243
DOI: 10.1055/s-2007-1013504
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© Georg Thieme Verlag, Stuttgart · New York

Effect of Gonadotropin Releasing Hormone on Ventral Prostate of Rat

V. S. Raju, V. Rukmini, P. R. K. Reddy
  • School of Life Sciences, University of Hyderabad, Hyderabad, India
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Publication History

1984

1984

Publication Date:
14 March 2008 (online)

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Summary

Testosterone induced increase in ornithine decarboxylase (ODC) activity was inhibited by simultaneous treatment with gonadotropin releasing hormone (GnRH) and its analogue in the ventral prostate of rat. Inhibition of 3H-uridine, 3H-phenylalanine and 3H-leucine incorporation into TCA precipitable material was also inhibited by GnRH in the dihydrotestosterone (DHT) treated animals. These studies further confirm that GnRH acts directly on ventral prostate and causes inhibitory effects.

Key-Words:

Gonadotropin Releasing Hormone - Ventral Prostate - Inhibition of Protein - RNA - Ornithine Decarboxylase Activity - Rat

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