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Horm Metab Res 1984; 16: 190-194
DOI: 10.1055/s-2007-1014931
IV. NEW FORMS OF TREATMENT
© Georg Thieme Verlag, Stuttgart · New York

Near Normalization of Metabolism of IDDM: Comparison of Continuous Subcutaneous (CSII) versus Intraperitoneal (CIPII) Insulin Delivery

B. R. Gooch, N. N. Abumrad, R. P. Robinson, O. B. Crofford
  • Departments of Medicine and Surgery, Vanderbilt University, School of Medicine, Nashville, Tennessee, U.S.A.
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Publication History

1983

1983

Publication Date:
14 March 2008 (online)

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Summary

The effects of continuous insulin infusion given subcutaneously (CSII) and intraperitoneally (CIPII) on 24 h “metabolic” profile of four insulin dependent diabetic volunteers were assessed. When the insulin dose delivered is adjusted to achieve a near match of the peripheral plasma glucose profile, the 24 h profiles of free fatty acids, glycerol, lactate and β-hydroxybutyrate and the hormones, insulin, glucagon, cortisol and catecholamines were identical.

These results suggest that CIPII has no advantage over CSII in normalizing of the metabolism of the insulin dependent diabetic.

Key-Words:

IDDM - Exercise - Insulin Delivery

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