Dtsch Med Wochenschr 2007; 132(45): 2383-2386
DOI: 10.1055/s-2007-991664
Prinzip & Perspektive | Review article
Infektiologie, Molekularbiologie
© Georg Thieme Verlag KG Stuttgart · New York

Neue Therapieansätze bei Malaria: molekulare Aspekte der Erythrozyteninvasion

New therapeutic approaches for malaria: molecular aspects of erythrocyte invasionT. Spielmann1 , T.-W Gilberger1
  • 1Bernhard-Nocht-Institut für Tropenmedizin, Abt. Molekulare Parasitologie, AG Malaria II
Further Information

Publication History

eingereicht: 13.8.2007

akzeptiert: 11.10.2007

Publication Date:
31 October 2007 (online)

Literatur

  • 1 Cowman A F, Crabb B S. Invasion of red blood cells by malaria parasites. Review.  Cell. 2006;  124 755-66
  • 2 Gardner M J, Hall N, Fung E . et al . Genome sequence of the malaria parasite plasmodium falciparum.  Nature. 2002;  416 498-511
  • 3 Good M F. Vaccine-induced immunity to malaria parasites and the need for novel strategies. Review.  Trends Parasitol. 2005;  21 29-34
  • 4 Kouyaté B, Sie A, Ye M, De Allegri M, Müller O. The Great Failure of Malaria Control in Africa: A District Perspective from Burkina Faso.  PLoS Med. 2007;  4 e127
  • 5 Kwiatkowski D P. How malaria has affected the human genome an what human genetics can teach us about malaria.  Am J Hum Genet. 2005;  77 171-192
  • 6 O’Donnell R A, Hackett F, Howell S A, Treeck M, Struck N, Krnajski Z, Withers-Martinez C, Gilberger T W, Blackman M J. Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.  J Cell Biol. 2006;  174 1023-33
  • 7 Snow R W, Guerra C A, Noor A M, Myint H Y, Hay S I. The global distribution of clinical episodes of Plasmodium falciparum malaria.  Nature. 2005;  434 214-7
  • 8 Sturm A, Amino R, van de Sand C, Regen T, Retzlaff S, Rennenberg A, Krueger A, Pollok J M, Menard R, Heussler V T. Manipulation of host hepatocytes by the malaria parasite for delivery into liver sinusoids.  Science. 2006;  313 1287-90

Dr. rer. nat. Tim-Wolf Gilberger

Bernhard-Nocht-Institut für Tropenmedizin

Bernhard-Nocht-Str. 74

20359 Hamburg,

Phone: +49 (0)40 / 42 818-486

Fax: +49 (0)40 / 42 818-400

Email: gilberger@bni-hamburg.de