PDF herunterladen
Thromb Haemost 2006; 95(03): 589-590
DOI: 10.1160/TH05-12-0806
Letters to the Editor
Schattauer GmbH

Thrombospondin-4 Ala387Pro polymorphism is not associated with vascular function and risk of coronary heart disease in US men and women

Folkert W. Asselbergs
1   Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
5   Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
,
Jennifer K. Pai
1   Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
2   Division of Preventive Medicine Boston, Massachusetts, USA
,
Tobias Pischon
4   Department of Epidemiology, German Institute of Human Nutrition, Postdam-Rehbruecke, Germany
,
JoAnn E. Manson
1   Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
2   Division of Preventive Medicine Boston, Massachusetts, USA
,
Eric B. Rimm
1   Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
3   Charming Laboratory, Department of Medicine, Brigham & Women’s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
› InstitutsangabenFinancial support: Dr. F.W. Asselbergs is a research fellow of the Netherlands Heart Foundation (2003T0I0) and the Dutch Inter University Cardiology Institute Netherlands. Ms. Pai is funded by an institutional training grant (HL07575) from the National Heart, Lung, and Blood institute. Dr. Pischon is a jetson Lincoln fellow, supported in part by an unrestricted grant from Lincoln.
Weitere Informationen

Publikationsverlauf

Received 18. Dezember 2005

Accepted after revision 26. Januar 2006

Publikationsdatum:
29. November 2017 (online)

    Lizenzen und Reprints

 

 

  • References

  • 1 Stenina OI. et al. Thrombospondin-4 and its variants: expression and differential effects on endothelial cells. Circulation 2003; 108: 1514-9.
    CrossrefPubMedGoogle Scholar
  • 2 Topol EJ. et al. Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 2001; 104: 2641-4.
    CrossrefPubMedGoogle Scholar
  • 3 McCarthy JJ. et al. Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes. J Med Genet 2004; 41: 334-41.
    CrossrefPubMedGoogle Scholar
  • 4 Boekholdt SM. et al. Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol 2002; 22: e24-e27.
    CrossrefPubMedGoogle Scholar
  • 5 Yamada Y. et al. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med 2002; 347: 1916-23.
    CrossrefPubMedGoogle Scholar
  • 6 Zhou X. et al. Thrombospondin-4 A387P polymorphism is not associated with coronary artery disease and myocardial infarction in the Chinese Han population. Clin Sci (Lond) 2004; 106: 495-500.
    CrossrefPubMedGoogle Scholar
  • 7 Cui J. et al. Gender dependent association of thrombospondin-4 A387P polymorphism with myocardial infarction. Arterioscler Thromb Vasc Biol 2004; 24: el83-el84.
    PubMedGoogle Scholar
  • 8 Wessel J. et al. Replication of the association between the thrombospondin-4 A387P polymorphism and myocardial infarction. Am Heart J 2004; 147: 905-9.
    CrossrefPubMedGoogle Scholar
  • 9 Pischon T. et al. Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women. Arterioscler Thromb Vasc Biol 2005; 25: 1654-8.
    CrossrefPubMedGoogle Scholar
  • 10 Meigs JB. et al. Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. JAMA 2004; 291: 1978-86.
    CrossrefPubMedGoogle Scholar
  • 11 Lewis CM. Genetic association studies: design. analysis and interpretation. Brief Bioinform 2002; 03: 146-53.
    CrossrefPubMedGoogle Scholar