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Synthesis 2014; 46(23): 3268-3272
DOI: 10.1055/s-0034-1378663
DOI: 10.1055/s-0034-1378663
paper
An Efficient Synthesis of 3,3′-Bipiperidines Using an ROM/RCM Metathesis Sequence: Extension to Oxygenated Analogues
Further Information
Publication History
Received: 14 March 2014
Accepted after revision: 18 July 2014
Publication Date:
28 August 2014 (online)
Dedicated to the memory of Dr. Hans Greuter
Abstract
A short and efficient diastereoselective synthesis of 3,3′-bipiperidine and 3,3′-bis(1,2,3,6-tetrahydropyridine) was accomplished using a tandem ring-opening metathesis/ring-closing metathesis (ROM/RCM) sequence as a key step. This strategy has been extended to the synthesis of the oxygenated analogues.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/products/ejournals/journal/ 10.1055/s-00000084.
- Supporting Information
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For a recent review on this field, see:
For related publications, see:
For an excellent recent review on this topic, see:
For recent reviews on this field, see:
For recent reviews on synthetic applications, see:
For recent representative examples, see:
For recent representative examples on ROM/RCM reaction sequence on cyclobutene-containing substrates, see: