CC BY-NC-ND 4.0 · Planta Medica International Open 2020; 07(03): e100-e105
DOI: 10.1055/a-1159-0738
Original Paper

Clinical and Microbiological Outcomes of Topical Aloe Vera Gel vs. Photochemotherapy as an Adjunct to Non-surgical Periodontal Treatment in Periodontitis

Mohamed Farouk Elsadek
1  Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
2  Nutrition and Food Science Department, Faculty of Home Economics, Helwan University, Cairo, Egypt
,
Badreldin Mohamed Ahmed
1  Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
,
Rayan M. Eskandrani
3  Clinical Specialist in Restorative Dentistry, Department of Restorative Dentistry, Ministry of Health Riyadh, Riyadh, Saudi Arabia
,
Tasneem Sobhy Fahmy
2  Nutrition and Food Science Department, Faculty of Home Economics, Helwan University, Cairo, Egypt
› Author Affiliations
Funding: The authors extend their appreciation to the Deanship of Scientific Research at King Saud University for funding this work through research group no (RG-1439-81).
  

Abstract

The present clinical trial aimed to assess the effectiveness of antimicrobial photodynamic therapy versus Aloe vera gel as an adjunct to scaling and root planing on periodontal and microbial outcomes in patients with periodontitis. Eligible patients undergoing nonsurgical periodontal treatment were divided into 3 groups: group 1: antimicrobial photodynamic therapy; group 2: Aloe vera gel application; and group 3: scaling and root planing only. Clinical periodontal variables included the assessment of plaque scores, bleeding on probing, probing depth, and clinical attachment level gain. Plaque samples were collected to estimate microbial counts of Tannerella forsythia (T. forsythia) and Porphyromonas gingivalis (P. gingivalis). All measurements were recorded at baseline, 3 mo, and 6 mo. Statistical analysis of the given data was performed using the chi-squared test and ANOVA for clinical periodontal and microbiological data. Eighty-seven patients completed the trial. Bleeding on probing showed a significant reduction in group 2 compared with the other groups (p < 0.001). Group 1 showed a statistically significant reduction in probing depth and gain in clinical attachment level when compared to group 2 and group 3 (p < 0.05). Group 1 showed a statistically significant reduction in the counts of T. forsythia and P. gingivalis over a period of 3 mo (p < 0.05). The reduction was seen for T. forsythia only following 6 mo (p < 0.05). Group 2 showed a significant reduction for only T. forsythia at 3 mo (p < 0.05). Both antimicrobial photodynamic therapy and Aloe vera gel helped in reducing periodontal inflammation. Aloe vera gel showed additional benefit in reducing bleeding scores, while antimicrobial photodynamic therapy showed additional enhanced activity against periodontal pathogens and periodontal attachment level gain.



Publication History

Received: 21 March 2020
Received: 03 April 2020

Accepted: 15 April 2020

Publication Date:
05 June 2020 (online)

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