Altersbedingte Makuladegeneration in einer alternden Gesellschaft – aktuelle epidemiologische Forschungsansätze und Erkenntnisse

Caroline Brandl; Robert Patrick Finger; Iris Maria Heid; Matthias Marten Mauschitz

doi:10.1055/a-2105-1064

Klinische Monatsblätter für Augenheilkunde, Table of Contents

Klin Monbl Augenheilkd 2023; 240(09): 1052-1059
DOI: 10.1055/a-2105-1064

Übersicht

Age-Related Macular Degeneration in an Ageing Society – Current Epidemiological Research

Article in several languages: deutsch | English

Caroline Brandl

¹Universitäts-Augenklinik Regensburg, Universität Regensburg, Fakultät für Medizin, Deutschland

²Lehrstuhl für Genetische Epidemiologie, Universität Regensburg, Fakultät für Medizin, Deutschland

,

Robert Patrick Finger

³Universitäts-Augenklinik, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim, Ruprecht-Karls-Universität Heidelberg, Mannheim, Deutschland

⁴Universitäts-Augenklinik Bonn, Universität Bonn, Deutschland

,

Iris Maria Heid

²Lehrstuhl für Genetische Epidemiologie, Universität Regensburg, Fakultät für Medizin, Deutschland

,

Matthias Marten Mauschitz

⁴Universitäts-Augenklinik Bonn, Universität Bonn, Deutschland

› Author Affiliations

Abstract

Epidemiological studies on age-related macular degeneration (AMD) provide crucial data on the frequency of early and late forms as well as associated risk factors. The increasing number of population-based cross-sectional and longitudinal cohort studies in Germany and Europe with published data is making prevalence and incidence estimators for AMD more robust, although they show mostly method-related fluctuations. This review article brings together the latest published epidemiological measures for AMD from Germany and Central as well as Western Europe. Based on this data and population figures for Germany and Europe, prevalence is projected, and future trends are forecasted. The epidemiological evidence for AMD-associated risk factors is also improving, especially through meta-analyses within large consortia with correspondingly high case numbers. This review article summarizes the latest findings and resulting recommendations for prevention approaches. Additionally, it discusses treatment options and future challenges.

Key words

age-related macular degeneration (AMD) - prevalence - incidence - risk factors - population-based studies - demographic development

Full Text

References

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