Multi-Functionalization of Solid Support via Zn(II)-Mediated Chirality-Directed Self-Assembly

Abstract

Establishing a strategy for realizing programmed self-assembly is critical in manufacturing materials with functional hybrid structures. In this work, we introduce a robust methodology for enabling multi-component self-assembly using the concept of chirality-directed self-assembly. A specific combination of heterochiral Zn(II) methylene bis(oxazoline) (BOX) complexes can be selectively generated when combinations of enantiomers of chiral BOX ligands are mixed in the presence of Zn(Oac)₂. The resulting Zn(II) BOX complexes, unlike non-covalent bonds, are highly stable and stay intact at elevated temperatures, yet can be reversibly disintegrated under mild conditions using EDTA. This approach can be easily applied to multi-functionalize various solid supports enabling the one-pot generation of multi-functional hybrid structures.

Key words

chirality-driven self-assembly - multi-functionalization - heterochiral metal–ligand complexes

Publication History

Received: 18 February 2023

Accepted after revision: 30 May 2023

Accepted Manuscript online:
06 June 2023

Article published online:
27 June 2023

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