Klin Monbl Augenheilkd 2024; 241(10): 1134-1139
DOI: 10.1055/a-2307-0363
Übersicht

Topical Atropine for Myopia Control: A Review

Topisches Atropin zur Myopieprävention: ein Review
Navid Farassat
Medical Center, Eye Center, University Freiburg, Germany
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Abstract

Over the past decade, atropine has emerged as an effective intervention for preventing myopia in children. Multiple randomized controlled trials, mainly from Asia, have demonstrated the safety and efficacy of topical atropine for myopia control. Both efficacy and side effects exhibit a positive dose-response relationship. This review focuses on new data from studies with predominantly white populations, ethnicity-dependent differences in efficacy and side effects, and primary prevention of incident myopia with atropine.

Zusammenfassung

In der letzten Dekade hat sich Atropin als wirksames Mittel zur Prävention von Myopie bei Kindern erwiesen. Mehrere randomisierte kontrollierte Studien, vor allem aus Asien, konnten die Sicherheit und Wirksamkeit von topischem Atropin bestätigen. Sowohl die Wirksamkeit als auch die Nebenwirkungen weisen eine positive Dosis-Wirkungs-Beziehung auf. Diese Übersichtsarbeit konzentriert sich auf neue Daten aus Studien mit überwiegend weißen Bevölkerungsgruppen, auf ethnisch bedingte Unterschiede in der Wirksamkeit und den Nebenwirkungen sowie auf die Primärprävention (Verhindern der Erstmanifestation) von Myopie mit Atropin.

Keywords

pediatric ophthalmology - myopia - myopia prevention - myopia control - myopia management - atropine

Schlüsselwörter

Kinderophthamologie - Myopie - Atropin - Myopieprävention


Publication History

Received: 05 April 2024

Accepted: 11 April 2024

Article published online:
27 May 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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