Am J Perinatol
DOI: 10.1055/a-2592-0430
Original Article

The Relationship between Hip Ultrasound Result and the Diagnosis of Developmental Dysplasia of the Hip in Premature Infants

1   Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio
,
Sara Conroy
2   Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, Ohio
3   Biostatistics Resource at Nationwide Children's Hospital, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio
4   The Ohio Perinatal Research Network, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio
,
1   Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio
4   The Ohio Perinatal Research Network, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio
› Author Affiliations

Funding This research is partially supported by funds from the Center for Perinatal Research, Abigail, Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Preview

Abstract

Objective

The study objective was to evaluate the relationship between the first hip ultrasound (HUS) result and developmental dysplasia of the hip (DDH) diagnosis in preterm infants. Additionally, we report the types of treatment for preterm infants diagnosed with DDH.

Study Design

This is a retrospective chart review of infants born between January 1, 2009, and December 31, 2018, at <37 weeks of gestation who had HUS in the first year of life. Positive predictive value (PPV), negative predictive value (NPV), sensitivity, and specificity for abnormal and normal HUS results were calculated.

Results

From 2,397 infants analyzed, 71 (3%) infants were diagnosed with DDH. The majority (n = 2,140; 89%) of patients had normal HUS, with only 5 (0.2%) infants later diagnosed with DDH. The sensitivity of HUS was 0.91 PPV 0.8, the specificity was 0.99 and NPV was 0.99. Of the 196 (8%) infants with equivocal results, 17 (9%) had subsequent DDH diagnoses.

For infants diagnosed with DDH, the majority (n = 41; 58%) were treated nonoperatively with Pavlik harness. Surgical correction was performed in 26 (36%) patients.

Conclusion

A normal first HUS result in preterm infants has an excellent NPV for the diagnosis of DDH. Abnormal first HUS has a good PPV. Those with an equivocal result may need close follow-up.

Key Points

  • A normal HUS in preterm infants strongly rules out DDH.

  • An abnormal HUS result in preterm infants has a good PPV for DDH.

  • Most preterm infants with developmental DDH are managed nonsurgically.



Publication History

Received: 13 November 2024

Accepted: 22 April 2025

Accepted Manuscript online:
23 April 2025

Article published online:
08 May 2025

© 2025. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA