Synlett
DOI: 10.1055/a-2685-9449
Letter

Enaminone-Directed Rh(III)-Catalyzed Hydroarylation Reaction of Oxa/azabenzonorbornadienes through C-H Bond Functionalization

Jitendra D. Belani
1   Pharmaceutical Sciences, College of Pharmacy, Thomas Jefferson University, Philadelphia, United States (Ringgold ID: RIN6559)
,
Milind M Ahire
1   Pharmaceutical Sciences, College of Pharmacy, Thomas Jefferson University, Philadelphia, United States (Ringgold ID: RIN6559)
› Author Affiliations
Preview

We report a Rh(III)-catalyzed hydroarylation of oxa-and azabenzonorbornadienes directed by enaminones through C-H activation. The reaction proceeds under mild conditions with broad substrate scope and excellent regioselectivity. Diverse polycyclic products are obtained in high yields. A representative structure was confirmed by X-ray analysis.



Publication History

Received: 25 July 2025

Accepted after revision: 18 August 2025

Accepted Manuscript online:
19 August 2025

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