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CC BY 4.0 · SynOpen
DOI: 10.1055/a-2713-6067
Graphical Review

Approaches to the Construction of Endocyclic Sulfoximines

Authors

  • Alexey V. Dobrydnev 

    1   Chemistry Department, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine (Ringgold ID: RIN111229)
    2   Scientific support department, Enamine Ltd, Kyiv, Ukraine (Ringgold ID: RIN376198)
    3   Scientific department, SMC Ecopharm Ltd, Kyiv, Ukraine
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Endocyclic sulfoximines are a relatively novel class of cyclic sulfoximines where the S(O)=N group is a part of a ring structure. They possess unique physicochemical and structural features, including three-dimensionality and chirality, amid chemical and thermal stability. This graphical review presents a comprehensive compilation of synthetic approaches toward endocyclic sulfoximines, organized by the type of reaction employed. The reaction conditions are presented in the most detailed way; the proposed reaction mechanisms and the catalytic cycles are also provided.



Publikationsverlauf

Eingereicht: 25. August 2025

Angenommen nach Revision: 29. September 2025

Accepted Manuscript online:
29. September 2025

© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

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