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DOI: 10.1055/a-2717-3893
Social Determinants of Health and Oxygen Use in Preterm Infants with Bronchopulmonary Dysplasia
Autor*innen
Abstract
Objective
This study aimed to evaluate the association between the Child Opportunity Index (COI) and postdischarge oxygen use in infants with bronchopulmonary dysplasia (BPD).
Study Design
Retrospective study of infants < 32 weeks' gestation with BPD, discharged on home oxygen from 2010 to 2022 and followed in a BPD clinic. Primary outcome was duration of oxygen use, secondary outcomes were emergency room (ER) visits, missed BPD appointments, and readmission.
Results
Of 145 infants included in the study, 88 (60.3%) infants were in the very low COI category. Mean (standard deviation) duration of home oxygen was 89.5 (92) days. Regression analysis did not show any significant association between COI and duration of home oxygen use. Number of ER visits, unplanned readmissions, and missed BPD appointments also did not vary significantly between the COI groups.
Conclusion
Our study did not show any significant association between COI and duration of home oxygen use in infants with BPD.
Key Points
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COI not associated with duration of oxygen use.
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Uneven groups may have affected our results.
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Additional research in this area is needed.
Publikationsverlauf
Eingereicht: 01. Juli 2025
Angenommen: 06. Oktober 2025
Artikel online veröffentlicht:
13. November 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
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References
- 1 Bell EF, Hintz SR, Hansen NI. et al; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Mortality, in-hospital morbidity, care practices, and 2-year outcomes for extremely preterm infants in the US, 2013-2018. JAMA 2022; 327 (03) 248-263
- 2 Doyle LW, Anderson PJ. Long-term outcomes of bronchopulmonary dysplasia. Semin Fetal Neonatal Med 2009; 14 (06) 391-395
- 3 Aoyama BC, Rice JL, McGrath-Morrow SA, Collaco JM. Mortality in outpatients with bronchopulmonary dysplasia. J Pediatr 2022; 241: 48-53.e1
- 4 Sun T, Yu HY, Yang M, Song YF, Fu JH. Risk of asthma in preterm infants with bronchopulmonary dysplasia: a systematic review and meta-analysis. World J Pediatr 2023; 19 (06) 549-556
- 5 Smith MA, Steurer MA, Mahendra M, Zinter MS, Keller RL. Sociodemographic factors associated with tracheostomy and mortality in bronchopulmonary dysplasia. Pediatr Pulmonol 2023; 58 (04) 1237-1246
- 6 Bushroe KM, Politi MC, Zaniletti I. et al. Social determinants of health and timing of tracheostomy for severe bronchopulmonary dysplasia. J Pediatr 2025; 277: 114379
- 7 Lewis TR, Kielt MJ, Walker VP. et al; Bronchopulmonary Dysplasia Collaborative. Association of racial disparities with in-hospital outcomes in severe bronchopulmonary dysplasia. JAMA Pediatr 2022; 176 (09) 852-859
- 8 Banwell E, Collaco JM, Oates GR. et al. Area deprivation and respiratory morbidities in children with bronchopulmonary dysplasia. Pediatr Pulmonol 2022; 57 (09) 2053-2059
- 9 Szeto JJ, Radack JK, DeMauro SB. et al. Environmental determinants of post-discharge acute respiratory illness among preterm infants with bronchopulmonary dysplasia. Int J Environ Res Public Health 2024; 21 (05) 648
- 10 Acevedo-Garcia D, McArdle N, Hardy EF. et al. The Child Opportunity Index: improving collaboration between community development and public health. Health Aff (Millwood) 2014; 33 (11) 1948-1957
- 11 Akande MY, Ramgopal S, Graham RJ, Goodman DM, Heneghan JA. Child Opportunity Index and emergent PICU readmissions: a retrospective, cross-sectional study of 43 U.S. hospitals. Pediatr Crit Care Med 2023; 24 (05) e213-e223
- 12 Heneghan JA, Goodman DM, Ramgopal S. Hospitalizations at United States children's hospitals and severity of illness by Neighborhood Child Opportunity Index. J Pediatr 2023; 254: 83-90.e8
- 13 McCrory MC, Akande M, Slain KN. et al; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Social Determinants of Health Subgroup. Child Opportunity Index and pediatric intensive care outcomes: a multicenter retrospective study in the United States. Pediatr Crit Care Med 2024; 25 (04) 323-334
- 14 Shennan AT, Dunn MS, Ohlsson A, Lennox K, Hoskins EM. Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. Pediatrics 1988; 82 (04) 527-532
- 15 Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 1978; 92 (04) 529-534
- 16 Walsh MC, Kliegman RM. Necrotizing enterocolitis: treatment based on staging criteria. Pediatr Clin North Am 1986; 33 (01) 179-201
- 17 diversitydatakids.org. 2023. “Child Opportunity Index 2.0 database. Accessed April 2021 at: https://data.diversitydatakids.org/dataset/coi20-child-opportunity-index-2-0-database
- 18 Korten I, Ramsey K, Latzin P. Air pollution during pregnancy and lung development in the child. Paediatr Respir Rev 2017; 21: 38-46
- 19 Sullivan BA, Doshi A, Chernyavskiy P. et al. Neighborhood deprivation and association with neonatal intensive care unit mortality and morbidity for extremely premature infants. JAMA Netw Open 2023; 6 (05) e2311761
- 20 Keller RL, Feng R, DeMauro SB. et al; Prematurity and Respiratory Outcomes Program. Bronchopulmonary dysplasia and perinatal characteristics predict 1-year respiratory outcomes in newborns born at extremely low gestational age: a prospective cohort study. J Pediatr 2017; 187: 89-97.e3
- 21 Simpson SJ, Turkovic L, Wilson AC. et al. Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort study. Lancet Child Adolesc Health 2018; 2 (05) 350-359
- 22 Caskey S, Gough A, Rowan S. et al. Structural and functional lung impairment in adult survivors of bronchopulmonary dysplasia. Ann Am Thorac Soc 2016; 13 (08) 1262-1270
- 23 Deschamps J, Boucekine M, Fayol L. et al. Neighborhood disadvantage and early respiratory outcomes in very preterm infants with bronchopulmonary dysplasia. J Pediatr 2021; 237: 177-182.e1
- 24 Nelin TD, Yang N, Radack J. et al. Associations of neighborhood social vulnerability with emergency department visits and readmissions among infants with bronchopulmonary dysplasia. J Perinatol 2023; 43 (10) 1308-1313
- 25 Kersten EE, Adler NE, Gottlieb L. et al. Neighborhood child opportunity and individual-level pediatric acute care use and diagnoses. Pediatrics 2018; 141 (05) e20172309
- 26 Feister J, Kan P, Lee HC, Sanders L. Readmission after neonatal intensive care unit discharge: the importance of social drivers of health. J Pediatr 2024; 270: 114014
- 27 Alizadeh F, Gauvreau K, Mayourian J. et al. Social drivers of health and pediatric extracorporeal membrane oxygenation outcomes. Pediatrics 2023; 152 (06) e2023061305
