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Synfacts 2008(11): 1175-1175  
DOI: 10.1055/s-0028-1083452
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Iridium-Catalyzed Hydrogenation of 7,8-Dihydro-quinolin-5(6H)-ones

Contributor(s): Hisashi Yamamoto, Pingfan Li
X.-B. Wang, W. Zeng, Y.-G. Zhou*
Dalian Institute of Chemical Physics, P. R. of China
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Publikationsdatum:
23. Oktober 2008 (online)

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Significance

Asymmetric hydrogenation of pyridine derivatives is a relatively new area. The current work represents one of the few methods to achieve excellent enantiomeric excesses for these reactions. The authors also pointed out some of the more challenging substrates for hydrogenation.