Synfacts 2008(12): 1306-1306  
DOI: 10.1055/s-0028-1087323
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Diastereoselective Radical Cyclization Towards Piperidinones

Contributor(s): Mark Lautens, Jane Panteleev
E. Godineau, K. Schenk, Y. Landais*
University Bordeaux 1, Talence, France; University of Lausanne, Switzerland
Further Information

Publication History

Publication Date:
20 November 2008 (online)


The authors report their findings on the radical cyclization of enoximes bearing an allylic chiral substitutent, extending on a preliminary study (Org. Lett. 2008, 8, 4871). Investigation of the role of steric and electronic parameters of the starting materials and further insight into the mechanism of the transformation are outlined in this comprehensive report.