Subscribe to RSS
Unsymmetrical Nickel-Catalyzed Oxidative Coupling of Terminal Alkynes
W. Yin, C. He, M. Chen, H. Zhang, A. Lei*
Wuhan University, P. R. of China
23 March 2009 (online)
A Ni/Cu-cocatalyzed oxidative coupling between two different terminal alkynes was discovered. NiCl2 and CuI are hereby supposed to catalyze the reaction in a synergistic way. Efficient heterocoupling was achieved by employing an excess of one terminal alkyne (five equivalents).