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DOI: 10.1055/s-0028-1109292
© Georg Thieme Verlag KG Stuttgart · New York
Capsular Opacification after Vitreous-Sparing Cataract Surgery in Children
Nachstarbildung bei Kindern nach Kataraktchirurgie unter Erhaltung des GlaskörpersPublication History
received: 26.9.2008
accepted: 20.11.2008
Publication Date:
21 April 2009 (online)

Zusammenfassung
Hintergrund: Kapseltrübungen nach Hinterkammerlinsen-Implantation (HKL-Implantation) sind bei Kindern wegen Amblyopierisiko gefürchtet. Eine hintere Kapsulotomie mit vorderer Vitrektomie hat sich zur Reduktion der Nachstarbildung nach Kataraktoperation bewährt, geht hingegen mit einem erhöhten Risiko eines Sekundärglaukoms einher. Patienten und Methoden: Diese Studie untersuchte die Nachstarbildung in 73 Augen von afrikanischen Kindern, bei welchen eine HKL zwischen 1998 und 2001 unter Erhaltung des Glaskörpers implantiert wurde. Die Haptik der HKL wurde in allen Augen in den Kapselsack implantiert, davon die Optik in den Kapselsack ohne Kapsulotomie in 12, mit Kapsulotomie in 14 und in Kombination mit der Knopflochtechnik in 47 Augen. Resultate: Die Bildung von Elschnig-Perlen hing signifikant von der Knopflochtechnik (p < 0,001) und vom Alter des Kindes (p < 0,05), nicht aber von der Kapsulotomie (p = 0,084) und der Augenseite (p = 0,1) ab. Die Klarheit der Sehachse wurde signifikant von der Knopflochtechnik (p < 0,001), nicht aber von der Kapsulotomie beeinflusst. Schlussfolgerungen: Eine hintere Kapsulotomie verhindert keine zentrale Nachstarbildung nach Kataraktoperation und HKL-Implantation bei Kindern, wenn der Glaskörper erhalten wurde, außer in Kombination mit der Knopflochtechnik.
Abstract
Background: The aim of this study was to evaluate different methods of intraocular lens (IOL) implantation and posterior capsule management in the absence of vitrectomy with respect to visual axis opacification (VAO) in children. Patients and Methods: Seventy-three eyes of African children undergoing cataract extraction and IOL implantation between 1998 and 2001 were evaluated. In all eyes, the IOL haptics were placed in the bag and the vitreous was preserved. The IOL optic and posterior capsule were managed in the following 3 ways: The IOL optic was captured behind the posterior capsule in conjunction with posterior capsulotomy (PC) in 47 eyes (group 1). The IOL optic was implanted in the bag with PC in 14 eyes (group 2) and without PC in 12 eyes (group 3). Cox proportional hazard analysis and Kaplan-Meier survival curves were performed to evaluate the incidence of Elschnig pearls (EP) and VAO. Results: Elschnig pearls developed in 14.9 % of the patients in group 1, in 56.8 % in group 2 and in 91.7 % in group 3. The occurrence of EP depended significantly on optic capture (p < 0.001) and child’s age (p < 0.05), but not on PC (p = 0.084) and eye side (p = 0.1). The persistence of visual axis clarity depended significantly on optic capture (p < 0.001) but not on PC. Conclusions: In vitreous-sparing cataract surgery, posterior capsule opening does not effectively prevent VAO unless it is in conjunction with IOL optic capture.
Schlüsselwörter
Hinterkammerlinsen - pädiatrische Katarakt - Knopflochtechnik - Nachstarbildung - Kapseltrübungen
Key words
intraocular lens - paediatric cataracts - optic capture - capsular opacification - visual axis opacification
References
- 1
Alexandrakis G, Peterseim M M, Wilson M E.
Clinical outcomes of pars plana capsulotomy with anterior vitrectomy in pediatric
cataract surgery.
J Aapos.
2002;
6
163-167
MissingFormLabel
- 2
Aslam T M, Dhillon B, Werghi N. et al .
Systems of analysis of posterior capsule opacification.
Br J Ophthalmol.
2002;
86
1181-1186
MissingFormLabel
- 3
Basti S, Ravishankar U, Gupta S.
Results of a prospective evaluation of three methods of management of pediatric cataracts.
Ophthalmology.
1996;
103
713-720
MissingFormLabel
- 4
Bender L, Spalton D J, Uyanonvara B. et al .
POCOman: new system for quantifying posterior capsule opacification.
J Cataract Refract Surg.
2004;
30
2058-2063
MissingFormLabel
- 5
BenEzra D, Cohen E.
Posterior capsulectomy in pediatric cataract surgery: the necessity of a choice.
Ophthalmology.
1997;
104
2168-2174
MissingFormLabel
- 6
Brady K M, Atkinson C S, Kilty L A. et al .
Cataract surgery and intraocular lens implantation in children.
Am J Ophthalmol.
1995;
120
1-9
MissingFormLabel
- 7
Buckley E G, Klombers L A, Seaber J H. et al .
Management of the posterior capsule during pediatric intraocular lens implantation.
Am J Ophthalmol.
1993;
115
722-728
MissingFormLabel
- 8
Dahan E.
Intraocular lens implantation in children.
Curr Opin Ophthalmol.
2000;
11
51-55
MissingFormLabel
- 9
Fenton S, O’Keefe M.
Primary posterior capsulorhexis without anterior vitrectomy in pediatric cataract
surgery: longer-term outcome.
J Cataract Refract Surg.
1999;
25
763-767
MissingFormLabel
- 10
Ghosh B, Gupta A K, Taneja S. et al .
Epilenticular lens implantation versus extracapsular cataract extraction and lens
implantation in children.
J Cataract Refract Surg.
1997;
23 (Suppl 1)
612-617
MissingFormLabel
- 11
Gimbel H V.
Posterior capsulorhexis with optic capture in pediatric cataract and intraocular lens
surgery.
Ophthalmology.
1996;
103
1871-1875
MissingFormLabel
- 12
Gimbel H V.
Posterior continuous curvilinear capsulorhexis and optic capture of the intraocular
lens to prevent secondary opacification in pediatric cataract surgery.
J Cataract Refract Surg.
1997;
23 (Suppl 1)
652-656
MissingFormLabel
- 13
Gimbel H V, DeBroff B M.
Posterior capsulorhexis with optic capture: maintaining a clear visual axis after
pediatric cataract surgery.
J Cataract Refract Surg.
1994;
20
658-664
MissingFormLabel
- 14
Gimbel H V, Ferensowicz M, Raanan M. et al .
Implantation in children.
J Pediatr Ophthalmol Strabismus.
1993;
30
69-79
MissingFormLabel
- 15
Grieshaber M C, Pienaar A, Stegmann R.
Posterior vertical capsulotomy with optic entrapment of the intraocular lens in congenital
cataracts – prevention of capsule opacification.
J Cataract Refract Surg.
2005;
31
886-894
MissingFormLabel
- 16
Guo S, Wagner R S, Caputo A.
Management of the anterior and posterior lens capsules and vitreous in pediatric cataract
surgery.
J Pediatr Ophthalmol Strabismus.
2004;
41
330-337; quiz 356 – 337
MissingFormLabel
- 17
Hiles D A, Hered R W.
Modern intraocular lens implants in children with new age limitations.
J Cataract Refract Surg.
1987;
13
493-497
MissingFormLabel
- 18
Hosal B M, Biglan A W.
Risk factors for secondary membrane formation after removal of pediatric cataract.
J Cataract Refract Surg.
2002;
28
302-309
MissingFormLabel
- 19
Jensen A A, Basti S, Greenwald M J. et al .
When may the posterior capsule be preserved in pediatric intraocular lens surgery?.
Ophthalmology.
2002;
109
324-327; discussion 328
MissingFormLabel
- 20
Knight-Nanan D, O’Keefe M, Bowell R.
Outcome and complications of intraocular lenses in children with cataract.
J Cataract Refract Surg.
1996;
22
730-736
MissingFormLabel
- 21
Koch D D, Kohnen T.
Retrospective comparison of techniques to prevent secondary cataract formation after
posterior chamber intraocular lens implantation in infants and children.
J Cataract Refract Surg.
1997;
23 (Suppl 1)
657-663
MissingFormLabel
- 22
Lambert S R, Drack A V.
Infantile cataracts.
Surv Ophthalmol.
1996;
40
427-458
MissingFormLabel
- 23
Mackool R J, Chhatiawala H.
Pediatric cataract surgery and intraocular lens implantation: a new technique for
preventing or excising postoperative secondary membranes.
J Cataract Refract Surg.
1991;
17
62-66
MissingFormLabel
- 24
Malukiewicz-Wisniewska G, Kaluzny J, Lesiewska-Junk H. et al .
Intraocular lens implantation in children and youth.
J Pediatr Ophthalmol Strabismus.
1999;
36
129-133
MissingFormLabel
- 25
Nishi O, Nishi K.
Preventing posterior capsule opacification by creating a discontinuous sharp bend
in the capsule.
J Cataract Refract Surg.
1999;
25
521-526
MissingFormLabel
- 26
Oliver M, Milstein A, Pollack A.
Posterior chamber lens implantation in infants and juveniles.
Eur J Implant Refract Surg.
1990;
2
309-314
MissingFormLabel
- 27
Parks M M.
Posterior lens capsulectomy during primary cataract surgery in children.
Ophthalmology.
1983;
90
344-345
MissingFormLabel
- 28
Plager D A, Lipsky S N, Snyder S K. et al .
Capsular management and refractive error in pediatric intraocular lenses.
Ophthalmology.
1997;
104
600-607
MissingFormLabel
- 29
Rabiah P K.
Frequency and predictors of glaucoma after pediatric cataract surgery.
Am J Ophthalmol.
2004;
137
30-37
MissingFormLabel
- 30
Raina U K, Gupta V, Arora R. et al .
Posterior continuous curvilinear capsulorhexis with and without optic capture of the
posterior chamber intraocular lens in the absence of vitrectomy.
J Pediatr Ophthalmol Strabismus.
2002;
39
278-287
MissingFormLabel
- 31
Ram J, Apple D J, Peng Q. et al .
Update on fixation of rigid and foldable posterior chamber intraocular lenses. Part
II: Choosing the correct haptic fixation and intraocular lens design to help eradicate
posterior capsule opacification.
Ophthalmology.
1999;
106
891-900
MissingFormLabel
- 32
Simons B D, Siatkowski R M, Schiffman J C. et al .
Surgical technique, visual outcome, and complications of pediatric intraocular lens
implantation.
J Pediatr Ophthalmol Strabismus.
1999;
36
118-124
MissingFormLabel
- 33
Smith S R, Daynes T, Hinckley M. et al .
The effect of lens edge design versus anterior capsule overlap on posterior capsule
opacification.
Am J Ophthalmol.
2004;
138
521-526
MissingFormLabel
- 34
Stager D R, Weakley Jr D R, Hunter J S.
Long-term rates of PCO following small incision foldable acrylic intraocular lens
implantation in children.
J Pediatr Ophthalmol Strabismus.
2002;
39
73-76
MissingFormLabel
- 35
Tassignon M J, De Groot Jr V, Vrensen G F.
Bag-in-the-lens implantation of intraocular lenses.
J Cataract Refract Surg.
2002;
28
1182-1188
MissingFormLabel
- 36 Therneau T M, Grambsch P M. Modeling Survival Data. Berlin; Springer Verlag 2000
MissingFormLabel
- 37
Vasavada A, Desai J.
Primary posterior capsulorhexis with and without anterior vitrectomy in congenital
cataracts.
J Cataract Refract Surg.
1997;
23 (Suppl 1)
645-651
MissingFormLabel
- 38
Vasavada A R, Nihalani B R.
Pediatric cataract surgery.
Curr Opin Ophthalmol.
2006;
17
54-61
MissingFormLabel
- 39
Vasavada A R, Trivedi R H, Singh R.
Necessity of vitrectomy when optic capture is performed in children older than 5 years.
J Cataract Refract Surg.
2001;
27
1185-1193
MissingFormLabel
- 40
Vishwanath M, Cheong-Leen R, Taylor D. et al .
Is early surgery for congenital cataract a risk factor for glaucoma?.
Br J Ophthalmol.
2004;
88
905-910
MissingFormLabel
- 41
Whitley E, Ball J.
Statistics review 4: sample size calculations.
Critical care (London, England).
2002;
6
335-341
MissingFormLabel
- 42
Wilson M E.
Intraocular lens implantation: has it become the standard of care for children?.
Ophthalmology.
1996;
103
1719-1720
MissingFormLabel
Matthias C. Grieshaber, MD, FEBO
Department of Ophthalmology, University Hospital Basel
Mittlere Straße 91
4031 Basel
Switzerland
Email: mgrieshaber@uhbs.ch