Synfacts 2009(7): 0812-0812  
DOI: 10.1055/s-0029-1217236
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Indium Oxide Nanoparticles for C-S Coupling of Aryl Halides with Thiols

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada, Hidetoshi Ohta
V. P. Reddy, A. V. Kumar, K. Swapna, K. R. Rao*
Indian Institute of Chemical Technology, Hyderabad, India
Further Information

Publication History

Publication Date:
22 June 2009 (online)


Commercially available indium ­oxide (In2O3) nanoparticles were found to catalyze the C-S cross-coupling of aryl halides 1 with aryl and alkyl thiols 2. Thus, the reaction of 1 with 2 was carried out in the presence of In2O3 nanoparticles and KOH in DMSO to give the corresponding aryl sulfides 3 (25 examples, 5-97% yield).