Subscribe to RSS
Stereoselective Formation of Seven-Membered Rings
T. Hashimoto, Y. Naganawa, K. Maruoka*
Kyoto University, Japan
22 June 2009 (online)
The authors report a highly diastereoselective Tiffeneau-Demjanov-type ring expansion for the formation of cycloheptanones possessing an all-carbon quaternary stereocenter. Using a chiral auxiliary approach the transformation could be carried out asymmetrically with control of remote stereocenters.