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Synfacts 2009(11): 1256-1256  
DOI: 10.1055/s-0029-1218037
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Direct Metal-Catalyst-Free Reductive Cou-pling of Boronic Acids and Tosylhydrazones

Contributor(s): Paul Knochel, Tobias Thaler
J. Barluenga*, M. Tomás-Gamasa, F. Aznar, C. Valdés*
Universidad de Oviedo, Spain
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Publication History

Publication Date:
22 October 2009 (online)

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Significance

The direct reductive coupling of ­boronic acids to tosylhydrazones is reported. ­Remarkably, this reaction proceeds efficiently without the use of a metal catalyst.