Suzuki-Miyaura Coupling through C-CN Bond Cleavage

D.-G. Yu; M. Yu; B.-T. Guan; B.-J. Li; Y. Zheng; Z.-H. Wu; Z.-J. Shi

doi:10.1055/s-0029-1218042

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Synfacts 2009(11): 1255-1255
DOI: 10.1055/s-0029-1218042

Metal-Mediated Synthesis

Suzuki-Miyaura Coupling through C-CN Bond Cleavage

Contributor(s): Paul Knochel, Tobias Thaler
D.-G. Yu, M. Yu, B.-T. Guan, B.-J. Li, Y. Zheng, Z.-H. Wu, Z.-J. Shi*
Peking University,Beijing, P. R. of China

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Publication History

Publication Date:
22 October 2009 (online)

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Significance

A Ni-catalyzed Suzuki-Miyaura coupling is reported proceeding through C-CN bond cleavage. Variously functionalized aryl nitriles could be efficiently arylated.