Synfacts 2009(12): 1305-1305  
DOI: 10.1055/s-0029-1218327
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (-)-Himandrine

Contributor(s): Philip Kocienski
M. Movassaghi*, M. Tjandra, J. Qi
Massachusetts Institute of Technology, Cambridge, USA
Further Information

Publication History

Publication Date:
20 November 2009 (online)


(-)-Himandrine was isolated from the bark of the tree Galbulimima belgraveana. Eight of the ten stereogenic centers were created by diastereoselective processes starting from just two stereogenic centers in fragments B and H.