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Synthesis of (-)-Himandrine
M. Movassaghi*, M. Tjandra, J. Qi
Massachusetts Institute of Technology, Cambridge, USA
20 November 2009 (online)
(-)-Himandrine was isolated from the bark of the tree Galbulimima belgraveana. Eight of the ten stereogenic centers were created by diastereoselective processes starting from just two stereogenic centers in fragments B and H.