ABSTRACT
We investigated whether the presence of symptoms predicts the timing of subsequent
spontaneous preterm birth in a cohort of women with cervical length (CL) <1.5 cm.
A retrospective cohort study was conducted that included patients from 23 to 28 weeks'
gestation with a CL <1.5 cm on routine ultrasound. Two groups were defined on the
basis of presenting symptoms at the time of the ultrasound examination: asymptomatic
patients and those with symptoms of preterm labor. The incidence of delivery within
2 weeks was determined for both groups. A total of 88 patients with CL <1.5 cm were
identified from an ultrasound database. There were 52 patients with CL <1.5 cm and
no symptoms. Of these, 1 (1.9%) delivered within 2 weeks. The remaining 36 patients
had a CL <1.5 cm and symptoms of preterm labor. Of these, 11 (30.6%) delivered within
2 weeks (relative risk 15.9, 95% confidence interval 2.1 to 118). Premature cervical
shortening at 23 to 28 weeks, in the absence of symptoms of preterm labor, is rarely
associated with preterm delivery within 2 weeks. Following those patients clinically
may prevent prolonged hospitalization and allow steroid administration closer to the
date of delivery.
KEYWORDS
Prematurity - preterm birth - preterm labor - ultrasound - short cervix
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Fadi G MirzaM.D.
Clinical Fellow in Maternal-Fetal Medicine, Division of Maternal-Fetal Medicine, Department
of Obstetrics and Gynecology, Columbia University Medical Center
622 West 168th Street, New York, NY 10032
eMail: fgm2107@columbia.edu