Iridium-Catalyzed Enantioselective 1,6-Addition

Significance

This work described an iridium-­catalyzed asymmetric 1,6-addition of arylboroxines to α,β,γ,δ-unsaturated carbonyl compounds by employing an iridium chiral diene complex. Various δ-arylated carbonyl compounds were obtained in high yields and enantioselectivity. Also, the authors elaborated the product in a short sequence to provide nature product and important building blocks.