Catalytic S_N2′-Selective Substitution of Allylic Chlorides with Arylboronic Esters

Significance

A copper-catalyzed selective S_N2′ arylation of allyl chlorides is achieved using aryl boronates as nucleophiles. The arylation products are obtained in high yield with various allyl chlorides and aryl boronates, tolerating a wide range of functional groups.