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Synfacts 2010(11): 1215-1215  
DOI: 10.1055/s-0030-1258712
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Microcin SF608

Contributor(s): Steven V. Ley, Philippa B. Cranwell
S. Diethelm, C. S. Schindler, E. M. Carreira*
ETH Zürich, Switzerland
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Publication History

Publication Date:
21 October 2010 (online)

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Significance

Microcin SF608, a member of the aeruginosin family, is a serine protease inhibitor isolated in 1999. It displays selective activity against serine protease trypsin over chymo­trypsin.