Synfacts 2011(1): 0089-0089  
DOI: 10.1055/s-0030-1259119
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Nickel(0)-Catalyzed 1,4-Diborylation of Conjugated Dienes

Contributor(s): Paul Knochel, Andreas J. Wagner
R. J. Ely, J. P. Morken*
Boston College, Chestnut Hill, USA
Further Information

Publication History

Publication Date:
21 December 2010 (online)


The Ni(cod)2/Cy3P catalyst system enables the catalytic stereoselective 1,4-diborylation of conjugated dienes with bis(pinacolato)diboron. The reaction proceeds efficiently at low catalyst loadings of 2.5 mol%.