Highly Stereoselective Preparation of Cycloheptane-1,3-diones

Significance

Herein, the preparation of a cycloheptane ring from 1,2-diketones with high stereoselectivity is reported. The reaction of the diketone with bis(iodozincio)methane leads stereoselectively to the cis-divinylcyclopropane-1,2-diol, which is then transformed into the corresponding cycloheptane derivative via Cope rearrangement.